Proteintech, 28844-1-AP, Phospho-MAP3K1 (Thr1400) Polyclonal antibody

Size: 20ul / 100ul The Phospho-MAP3K1 (Thr1400) (28844-1-AP) by Proteintech is a Polyclonal antibody targeting Phospho-MAP3K1 (Thr1400) in WB, ELISA applications with reactivity to Human samples 28844-1-AP targets Phospho-MAP3K1 (Thr1400) in WB, ELISA applications and shows reactivity with Human samples. Tested Applications Positive WB detected in: Calyculin A treated HeLa cells Recommended dilution Western Blot (WB): WB : 1:2000-1:10000 Background Information MAP3K1, also named as MAPKKK1, MEKK and MEKK1, belongs to the protein kinase superfamily, STE Ser/Thr protein kinase family and MAP kinase kinase kinase subfamily. MAP3K1 is a component of a protein kinase signal transduction cascade. It activates CHUK and IKBKB, the central protein kinases of the NF-kappa-B pathway. MAP3K1 activates the ERK and JNK kinase pathways by phosphorylation of MAP2K1 and MAP2K4. MAP3K1 is activated by autophosphorylation on Thr-1400 and Thr-1412(Uniprot). Specification Tested Reactivity: Human Cited Reactivity: human, rat Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: Peptide Predict reactive species Full Name: mitogen-activated protein kinase kinase kinase 1 Calculated Molecular Weight: 164 kDa Observed Molecular Weight: 164 kDa GenBank Accession Number: NM_005921 Gene Symbol: MAP3K1 Gene ID (NCBI): 4214 RRID: AB_2918209 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity purification UNIPROT ID: Q13233 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.