Proteintech, 28846-1-AP, Phospho-ASK1 (Ser966) Polyclonal antibody

Size: 20ul / 100ul The Phospho-ASK1 (Ser966) (28846-1-AP) by Proteintech is a Polyclonal antibody targeting Phospho-ASK1 (Ser966) in WB, ELISA applications with reactivity to Human, Mouse samples 28846-1-AP targets Phospho-ASK1 (Ser966) in WB, ELISA applications and shows reactivity with Human, Mouse samples. Tested Applications Positive WB detected in: λ phosphatase treated NIH/3T3 cells Recommended dilution Western Blot (WB): WB : 1:500-1:1000 Background Information ASK1(Apoptosis signal-regulating kinase 1) is also named as MAP3K5, MAPKKK5, MEKK5 and belongs to the MAP kinase kinase kinase subfamily. It is an evolutionarily conserved mitogen activated protein 3-kinase that activates both Jnk and p38 mitogen-activated protein kinases. ASK1 is is activated in response to various cytotoxic stresses including TNF, Fas and reactive oxygen species (ROS) such as H2O2, and activates c-Jun NH 2-terminal kinase (JNK) and p38. The predicted MW of ASK1 is around 155 kDa and the 110-120 kDa fragment has also been reported. Specification Tested Reactivity: Human, Mouse Cited Reactivity: human, mouse, rat Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: Peptide Predict reactive species Full Name: mitogen-activated protein kinase kinase kinase 5 Calculated Molecular Weight: 155 kDa Observed Molecular Weight: 120 kDa GenBank Accession Number: BC054503 Gene Symbol: ASK1 Gene ID (NCBI): 4217 RRID: AB_2881220 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity purification UNIPROT ID: Q99683 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.