Proteintech, 28930-1-AP, Phospho-MEK1 (Thr292) Polyclonal antibody

Size: 20ul / 100ul The Phospho-MEK1 (Thr292) (28930-1-AP) by Proteintech is a Polyclonal antibody targeting Phospho-MEK1 (Thr292) in WB, ELISA applications with reactivity to Human samples 28930-1-AP targets Phospho-MEK1 (Thr292) in WB, IHC, ELISA applications and shows reactivity with Human samples. Tested Applications Positive WB detected in: nocodazole treated A431 cells Recommended dilution Western Blot (WB): WB : 1:1000-1:4000 Background Information MEK1 is also named as MAP2K1 (mitogen-activated protein kinase kinase 1), MAPKK1, PRKMK1, MKK1 and belongs to the MAP kinase kinase subfamily. It is a dual-specificity kinase that mediate ERK1 and ERK2 activation during adhesion and growth factor signaling(PMID:19219045). It also plays an essential role in extra-embryonic ectoderm during placentogenesis. MEK1 has 2 isoforms produced by alternative splicing with the molecular weight of 43 kDa and 41 kDa. MEK1 may form a heterodimer with Mek2.(PMID:21144847,19219045). Specification Tested Reactivity: Human Cited Reactivity: human, mouse Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: Peptide Predict reactive species Full Name: mitogen-activated protein kinase kinase 1 Calculated Molecular Weight: 43 kDa Observed Molecular Weight: 45-50 kDa GenBank Accession Number: BC139729 Gene Symbol: MEK1 Gene ID (NCBI): 5604 ENSEMBL Gene ID: ENSG00000169032 RRID: AB_2918216 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity purification UNIPROT ID: Q02750 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.