Proteintech, 29603-1-AP, BICD2 Polyclonal antibody

Size: 20ul / 150ul The BICD2 (29603-1-AP) by Proteintech is a Polyclonal antibody targeting BICD2 in WB, ELISA applications with reactivity to Human samples 29603-1-AP targets BICD2 in WB, ELISA applications and shows reactivity with Human samples. Tested Applications Positive WB detected in: A549 cells, Hela cells, Jurkat cells, K-562 cells, MCF-7 cells Recommended dilution Western Blot (WB): WB : 1:1000-1:4000 Background Information Protein bicaudal D homolog 2 (BICD2) acts as an adapter protein linking the dynein motor complex to various cargos and converts dynein from a non-processive to a highly processive motor in the presence of dynactin. Facilitates and stabilizes the interaction between dynein and dynactin and activates dynein processivity (the ability to move along a microtubule for a long distance without falling off the track). Facilitates the binding of RAB6A to the Golgi by stabilizing its GTP-bound form. Regulates coat complex coatomer protein I (COPI)-independent Golgi-endoplasmic reticulum transport via its interaction with RAB6A and recruitment of the dynein-dynactin motor complex (PubMed:25962623). Specification Tested Reactivity: Human Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: CatNo: Ag31279 Product name: Recombinant human BICD2 protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 361-523 aa of BC073970 Sequence: GLLATLQDTQKQLEHTRGSLSEQQEKVTRLTENLSALRRLQASKERQTALDNEKDRDSHEDGDYYEVDINGPEILACKYHVAVAEAGELREQLKALRSTHEAREAQHAEEKGRYEAEGQALTEKVSLLEKASRQDRELLARLEKELKKVSDVAGETQGSLSVA Predict reactive species Full Name: bicaudal D homolog 2 (Drosophila) Calculated Molecular Weight: 855 aa, 97 kDa Observed Molecular Weight: 93-96 kDa GenBank Accession Number: BC073970 Gene Symbol: BICD2 Gene ID (NCBI): 23299 RRID: AB_2935474 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity purification UNIPROT ID: Q8TD16 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.