Proteintech, 29946-1-AP, MYD88 Polyclonal antibody

Size: 20ul / 150ul The MYD88 (29946-1-AP) by Proteintech is a Polyclonal antibody targeting MYD88 in WB, IHC, ELISA applications with reactivity to mouse, rat samples 29946-1-AP targets MYD88 in WB, IHC, IF, ELISA applications and shows reactivity with mouse, rat samples. Tested Applications Positive WB detected in: NR8383 cells, RAW 264.7 cells, mouse liver tissue, rat liver tissue Positive IHC detected in: mouse liver tissueNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0 Recommended dilution Western Blot (WB): WB : 1:500-1:3000 Immunohistochemistry (IHC): IHC : 1:400-1:1600 Background Information MYD88 is a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. MYD88 is the key adaptor protein for the interleukin-1 receptor (IL-1R) and most Toll-like receptors (TLRs), which are essential for innate immunity and pathogen-associated molecular pattern recognition. Mutations in the MyD88 gene lead to the development of cancer in humans and mice suggesting that MyD88 also plays a cell autonomous role in tissue homeostasis. MYD88 is detected in bone marrow. Specification Tested Reactivity: mouse, rat Cited Reactivity: mouse, rat Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: CatNo: Ag30662 Product name: Recombinant mouse MYD88 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 50-150 aa of NM_010851 Sequence: LAEEMGFEYLEIRELETRPDPTRSLLDAWQGRSGASVGRLLELLALLDREDILKELKSRIEEDCQKYLGKQQNQESEKPLQVARVESSVPQTKELGGITTL Predict reactive species Full Name: myeloid differentiation primary response gene 88 Calculated Molecular Weight: 34 kDa Observed Molecular Weight: 29-34 kDa GenBank Accession Number: NM_010851 Gene Symbol: Myd88 Gene ID (NCBI): 17874 RRID: AB_3076471 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity purification UNIPROT ID: P22366 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.