Proteintech, 30301-1-AP, TMEM106B (122-140aa) Polyclonal antibody

Size: 20ul / 150ul The TMEM106B (122-140aa) (30301-1-AP) by Proteintech is a Polyclonal antibody targeting TMEM106B (122-140aa) in WB, ELISA applications with reactivity to Human samples 30301-1-AP targets TMEM106B (122-140aa) in WB, ELISA applications and shows reactivity with Human samples. Tested Applications Positive WB detected in: A549 cells, HeLa cells Recommended dilution Western Blot (WB): WB : 1:500-1:2000 Background Information TMEM106B is a genetic risk factor for frontotemporal lobar degeneration with TDP-43 inclusions (FTLD-TDP). Amyotrophic lateral sclerosis (ALS), like FTLD-TDP, is characterized by pathological TDP-43 inclusions. TMEM106B expression in the brain may be linked to mechanisms of disease in FTLD-TDP and risk alleles confer genetic susceptibility by increasing gene expression. TMEM106B can be showed as 31-55 kDa and 70-90 kDa (Glycosylated or Dimer) form in western blot test. (PMID: 27543298, 22895706, PMID: 23136129). Specification Tested Reactivity: Human Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: Peptide Predict reactive species Full Name: transmembrane protein 106B Calculated Molecular Weight: 31 kDa Observed Molecular Weight: 45 kDa GenBank Accession Number: BC033901 Gene Symbol: TMEM106B Gene ID (NCBI): 54664 RRID: AB_3086291 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity purification UNIPROT ID: Q9NUM4 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.