Proteintech, 30692-1-AP, IQGAP2 Polyclonal antibody

Size: 20ul / 150ul The IQGAP2 (30692-1-AP) by Proteintech is a Polyclonal antibody targeting IQGAP2 in WB, IHC, ELISA applications with reactivity to human, mouse samples 30692-1-AP targets IQGAP2 in WB, IHC, ELISA applications and shows reactivity with human, mouse samples. Tested Applications Positive WB detected in: HepG2 cells, HuH-7 cells, Ramos cells, human peripheral blood platelets, mouse testis tissue Positive IHC detected in: human stomach tissue, human intrahepatic cholangiocarcinoma tissue, mouse stomach tissueNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0 Recommended dilution Western Blot (WB): WB : 1:500-1:2000 Immunohistochemistry (IHC): IHC : 1:50-1:500 Background Information IQGAP2, a member of the IQGAP family, functions as a tumor suppressor in most of the cancers. IQGAP2 contains three IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. IQGAP2 interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. It also acts as a tumor suppressor and has been found to play a role in regulating innate antiviral responses. Specification Tested Reactivity: human, mouse Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: CatNo: Ag33518 Product name: Recombinant human IQGAP2 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 519-727 aa of NM_006633 Sequence: DEIQQAVDDANVDKDRAKQWVTLVVDVNQCLEGKKSSDILSVLKSSTSNANDIIPECADKYYDALVKAKELKSERVSSDGSWLKLNLHKKYDYYYNTDSKESSWVTPESCLYKESWLTGKEIEDIIEEVTVGYIRENIWSASEELLLRFQATSSGPILREEFEARKSFLHEQEENVVKIQAFWKGYKQRKEYMHRRQTFIDNTDSIVKI Predict reactive species Full Name: IQ motif containing GTPase activating protein 2 Calculated Molecular Weight: 181 kDa Observed Molecular Weight: 181 kDa GenBank Accession Number: NM_006633 Gene Symbol: IQGAP2 Gene ID (NCBI): 10788 RRID: AB_3086388 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity purification UNIPROT ID: Q13576 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.