Proteintech, 30696-1-AP, DFNA5/GSDME Polyclonal antibody

Size: 20ul / 150ul The DFNA5/GSDME (30696-1-AP) by Proteintech is a Polyclonal antibody targeting DFNA5/GSDME in WB, ELISA applications with reactivity to mouse, rat samples 30696-1-AP targets DFNA5/GSDME in WB, ELISA applications and shows reactivity with mouse, rat samples. Tested Applications Positive WB detected in: Neuro-2a cells, J774A.1 cells, mouse brain tissue, rat brain tissue Recommended dilution Western Blot (WB): WB : 1:500-1:2000 Background Information DFNA5 (deafness, autosomal dominant 5), also known as GSDME or ICERE-1, is a 496 amino acid protein that is expressed in cochlea tissue, as well as in placenta, brain, heart, liver, lung and pancreas. Defects in the gene encoding DFNA5 are the cause of non-syndromic sensorineural deafness autosomal dominant type 5 (DFNA5), a form of sensorineural hearing loss that results from damage to one of various structures that receive sound information in the brain. 30696-1-AP can detect full-length GSDME and cleaved GSDME. Specification Tested Reactivity: mouse, rat Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: CatNo: Ag33622 Product name: Recombinant mouse Dfna5 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-200 aa of BC132303 Sequence: MFAKATRNFLKEVDAGGDLISVSHLNDSDKLQLLSLVTKKKRYWCWQRPKYQILSATLEDVLTEGHCLSPVVVESDFVKYESKCENHKSGAIGTVVGKVKLNVGGKGVVESHSSFGTLRKQEVDVQQLIQDAVKRTVNMDNLVLQQVLESRNEVLCVLTQKIMTTQKCVISEHVQSEETCGGMVGIQTKTIQVSATEDGT* Predict reactive species Full Name: deafness, autosomal dominant 5 (human) Calculated Molecular Weight: 57 kDa Observed Molecular Weight: 57 kDa, 35 kDa GenBank Accession Number: BC132303 Gene Symbol: DFNA5/GSDME Gene ID (NCBI): 54722 RRID: AB_3669751 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity purification UNIPROT ID: Q9Z2D3 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.