Product Description
Size: 20ul / 150ul
The PTPRM/RPTPmu (30763-1-AP) by Proteintech is a Polyclonal antibody targeting PTPRM/RPTPmu in WB, ELISA applications with reactivity to human, rat samples
30763-1-AP targets PTPRM/RPTPmu in WB, ELISA applications and shows reactivity with human, rat samples.
Tested Applications
Positive WB detected in: MCF-7 cells, MDA-MB-231 cells, U-87 MG cells, rat eye tissue
Recommended dilution
Western Blot (WB): WB : 1:500-1:3000
Background Information
PTPRM, also known as protein tyrosine phosphatase receptor type M or RPTPmu, is a protein with a molecular weight of approximately 155 kDa. It is a receptor-type tyrosine phosphatase involved in cell-cell adhesion, migration, and signaling. It exists in two forms, either a full-length 200 kDa form or as two noncovalently associated fragments of 100 kDa each.Additional unidentified serine proteases cleave PTPμ in GBM cells to yield smaller extracellular fragments with MWs of 78 and 55 kDa (PMID: 25223585).
Specification
Tested Reactivity: human, rat
Host / Isotype: Rabbit / IgG
Class: Polyclonal
Type: Antibody
Immunogen: CatNo: Ag33475 Product name: Recombinant human PTPRM protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 765-880 aa of NM_002845 Sequence: KKRKLAKKRKETMSSTRQEMTVMVNSMDKSYAEQGTNCDEAFSFMDTHNLNGRSVSSPSSFTMKTNTLSTSVPNSYYPDETHTMASDTSSLVQSHTYKKREPADVPYQTGQLHPAI Predict reactive species
Full Name: protein tyrosine phosphatase, receptor type, M
Calculated Molecular Weight: 164KD
Observed Molecular Weight: 80 kDa, 100 kDa, 200 kDa
GenBank Accession Number: NM_002845
Gene Symbol: PTPRM
Gene ID (NCBI): 5797
Conjugate: Unconjugated
Form: Liquid
Purification Method: Antigen affinity purification
UNIPROT ID: P28827
Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.
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Collaboration
Tony Tang
Email: Tony.Tang@iright.com
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