Product Description
Size: 20ul / 150ul
The COQ2 (30909-1-AP) by Proteintech is a Polyclonal antibody targeting COQ2 in WB, ELISA applications with reactivity to Human samples
30909-1-AP targets COQ2 in WB, ELISA applications and shows reactivity with Human samples.
Tested Applications
Positive WB detected in: HEK-293 cells, U-87 MG cells
Recommended dilution
Western Blot (WB): WB : 1:1000-1:4000
Background Information
COQ2 (coenzyme Q2, polyprenyltransferase), also known as CL640. It is expected to be located in mitochondrion inner membrane. And the protein is highly expressed in skeletal muscle, adrenal glands and the heart. COQ2 is a redox carrier in the mitochondrial respiratory chain and a lipid-soluble antioxidant. This enzyme, which is part of the coenzyme Q10 pathway, catalyzes the prenylation of parahydroxybenzoate with an all-trans polyprenyl group. Mutations in this gene cause coenzyme Q10 deficiency, a mitochondrial encephalomyopathy, and also COQ2 nephropathy, an inherited form of mitochondriopathy with primary renal involvement. The protein has three isforms, the calculated molecular weight are 35, 40, 45 kDa.
Specification
Tested Reactivity: Human
Host / Isotype: Rabbit / IgG
Class: Polyclonal
Type: Antibody
Immunogen: CatNo: Ag29155 Product name: Recombinant human COQ2 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 35-146 aa of BC008804 Sequence: AGAPHGGDLQPPACPEPRGRQLSLSAAAVVDSAPRPLQPYLRLMRLDKPIGTWLLYLPCTWSIGLAAEPGCFPDWYMLSLFGTGAILMRGAGCTINDMWDQDYDKKVTRTAN Predict reactive species
Full Name: coenzyme Q2 homolog, prenyltransferase (yeast)
Calculated Molecular Weight: 371 aa, 40 kDa
Observed Molecular Weight: 35 kDa,40 kDa,45 kDa
GenBank Accession Number: BC008804
Gene Symbol: COQ2
Gene ID (NCBI): 27235
RRID: AB_3669780
Conjugate: Unconjugated
Form: Liquid
Purification Method: Antigen affinity Purification
UNIPROT ID: Q96H96
Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.
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Collaboration
Tony Tang
Email: Tony.Tang@iright.com
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