Product Description
Size: 20ul / 150ul
The INTS8 (31038-1-AP) by Proteintech is a Polyclonal antibody targeting INTS8 in WB, ELISA applications with reactivity to Human samples
31038-1-AP targets INTS8 in WB, ELISA applications and shows reactivity with Human samples.
Tested Applications
Positive WB detected in: HeLa cells, HuH-7 cells, MCF-7 cells
Recommended dilution
Western Blot (WB): WB : 1:1000-1:5000
Background Information
Integrator complex subunit 8 (INTS8) is one of the major components of RNA polymerase II and has been demonstrated to be involved in the cleavage of small nuclear RNAs and transcriptional processes (PMID: 34880328). INTS8 was robustly increased in neurodevelopmental diseases and numerous tumors. High INTS8 expression has a tight correlation with poor prognosis in multi-cancers (PMID: 30881114). Western blot analysis detected INTS8 at an apparent molecular mass of 111 kDa.
Specification
Tested Reactivity: Human
Host / Isotype: Rabbit / IgG
Class: Polyclonal
Type: Antibody
Immunogen: CatNo: Ag34627 Product name: Recombinant human INTS8 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 896-995 aa of BC136754 Sequence: QVAILCQFLREIDYKTAFKSLQEQNSHDAMDSYYDYIWDVTILEYLTYLHHKRGETDKRQIAIKAIGQTELNASNPEEVLQLAAQRRKKKFLQAMAKLYF Predict reactive species
Full Name: integrator complex subunit 8
Calculated Molecular Weight: 111 kDa
Observed Molecular Weight: 111 kDa
GenBank Accession Number: BC136754
Gene Symbol: INTS8
Gene ID (NCBI): 55656
RRID: AB_3669824
Conjugate: Unconjugated
Form: Liquid
Purification Method: Antigen affinity purification
UNIPROT ID: Q75QN2
Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.
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Collaboration
Tony Tang
Email: Tony.Tang@iright.com
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