Product Description
Size: 20ul / 150ul
The CD229/SLAMF3 (31717-1-AP) by Proteintech is a Polyclonal antibody targeting CD229/SLAMF3 in WB, ELISA applications with reactivity to human samples
31717-1-AP targets CD229/SLAMF3 in WB, ELISA applications and shows reactivity with human samples.
Tested Applications
Positive WB detected in: U266 cells
Recommended dilution
Western Blot (WB): WB : 1:2000-1:16000
Background Information
Signaling lymphocytic activation molecule 3 (SLAMF3), also known as CD229 or Ly9, is a type I transmembrane glycoprotein that belongs to the SLAM family receptors (PMID: 10970093; 15905546). It is composed of an extracellular region, which consists of four Ig-like domains, a transmembrane region, and a cytoplasmic tail, which includes two immunoreceptor tyrosine-based signaling motifs (ITSMs) and other tyrosine residues that act as binding sites for the SH2 structural domains (PMID: 8537117; 11369645; 38626547). SLAMF3 is mainly expressed in immune cells, such as T, B, and natural killer cells, and it is involved in the fundamental activation and suppression of these immune cells, as well as the regulation of complex immune networks (PMID: 38626547).
Specification
Tested Reactivity: human
Host / Isotype: Rabbit / IgG
Class: Polyclonal
Type: Antibody
Immunogen: CatNo: Ag34617 Product name: Recombinant human LY9 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 227-405 aa of BC121049 Sequence: KRKGRCSVPAFCSSQAEAPADTPEPTAGHTLYSVLSQGYEKLDTPLRPARQQPTPTSDSSSDSNLTTEEDEDRPEVHKPISGRYEVFDQVTQEGAGHDPAPEGQADYDPVTPYVTEVESVVGENTVYAQVFNLQGKTPVSQKEESSATIYCSIRKPQVVPPPQQNDLEIPESPTYENFT Predict reactive species
Full Name: lymphocyte antigen 9
Observed Molecular Weight: 90 kDa, 110 kDa
GenBank Accession Number: BC121049
Gene Symbol: LY9
Gene ID (NCBI): 4063
RRID: AB_3670094
Conjugate: Unconjugated
Form: Liquid
Purification Method: Antigen affinity purification
UNIPROT ID: Q9HBG7
Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.
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Collaboration
Tony Tang
Email: Tony.Tang@iright.com
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