Product Description
Size: 20ul / 150ul
The EFCAB4A (32115-1-AP) by Proteintech is a Polyclonal antibody targeting EFCAB4A in WB, ELISA applications with reactivity to human samples
32115-1-AP targets EFCAB4A in WB, ELISA applications and shows reactivity with human samples.
Tested Applications
Positive WB detected in: LNCaP cells
Recommended dilution
Western Blot (WB): WB : 1:1000-1:6000
Background Information
EFCAB4A (EF-hand calcium-binding domain-containing protein 4A), also known as CRACR2B (calcium release-activated calcium channel regulator 2B), is a calcium-binding protein containing EF-hand structural domain. EFCAB4A is thought to play a key role in calcium bank-manipulated calcium endocytosis (SOCE) in T cells by regulating activation of CRAC (calcium release-activated calcium channel) channels. This protein may perform a similar function to EFCAB4B, which acts as a cytoplasmic calcium sensor that forms a complex with ORAI1 and STIM1 in the region of the junction between the endoplasmic reticulum and the plasma membrane. The EFCAB4A protein contains two EF-hand structural domains, which may be involved in calcium bank-manipulated calcium endocytosis.
Specification
Tested Reactivity: human
Host / Isotype: Rabbit / IgG
Class: Polyclonal
Type: Antibody
Immunogen: CatNo: Ag37031 Product name: Recombinant human EFCAB4A protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 100-255 aa of BC033196 Sequence: SAQGANPCRTPEETFESGGLDVQGTAGSLDEEEEEEERFHTVLEQLGVAPVLGEQRAVRTLWARLQRERPELLGSFEDVLIRASACLEEAARERDGLEQALRRRESEHEREVRALYEETEQLREQSRRPPSQNFARGERRSRLELELQIREQDLER Predict reactive species
Full Name: EF-hand calcium binding domain 4A
Observed Molecular Weight: 50 kDa
GenBank Accession Number: BC033196
Gene Symbol: EFCAB4A
Gene ID (NCBI): 283229
Conjugate: Unconjugated
Form: Liquid
Purification Method: Antigen affinity Purification
UNIPROT ID: Q8N4Y2
Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.
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Collaboration
Tony Tang
Email: Tony.Tang@iright.com
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