Product Description
Size: 20ul / 150ul
The ARHGAP44 (32382-1-AP) by Proteintech is a Polyclonal antibody targeting ARHGAP44 in WB, IHC, IF/ICC, ELISA applications with reactivity to human, rat samples
32382-1-AP targets ARHGAP44 in WB, IHC, IF/ICC, ELISA applications and shows reactivity with human, rat samples.
Tested Applications
Positive WB detected in: HEK-293 cells, rat brain tissue, LNCaP cells
Positive IHC detected in: human urothelial carcinoma tissueNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0
Positive IF/ICC detected in: HEK-293 cells
Recommended dilution
Western Blot (WB): WB : 1:5000-1:50000
Immunohistochemistry (IHC): IHC : 1:750-1:3000
Immunofluorescence (IF)/ICC: IF/ICC : 1:200-1:800
Background Information
Rho GTPase-activating protein 44 (ARHGAP44) belongs to the Rho GTPase-activating protein (RhoGAP) family, also known as Rich2.ARHGAP44 plays an important role in cytoskeletal dynamics, cellular motility and signaling. Its high expression in osteosarcoma correlates with tumor malignancy, suggesting its potential as a potential therapeutic target. In addition, ARHGAP44 may also be involved in the pathogenesis of diabetes and cardiovascular diseases, and its specific role in these diseases needs to be further investigated in the future.
Specification
Tested Reactivity: human, rat
Host / Isotype: Rabbit / IgG
Class: Polyclonal
Type: Antibody
Immunogen: CatNo: Ag38196 Product name: Recombinant human ARHGAP44 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 580-772 aa of NM_001321166 Sequence: LQPGPERTSTTKSKELSPGSAQKGSPGSSQGTACAGTQPGAQPGAQPGASPSPSQPPADQSPHTLRKVSKKLAPIPPKVPFGQPGAMADQSAGQPSPVSLSPTPPSTPSPYGLSYPQGYSLASGQLSPAAAPPLASPSVFTSTLSKSRPTPKPRQRPTLPPPQPPTVNLSASSPQSTEAPMLDGMSPGESMST Predict reactive species
Full Name: Rho-type GTPase-activating protein RICH2
Calculated Molecular Weight: 818aa, 89 kDa
Observed Molecular Weight: 80-100 kDa
GenBank Accession Number: NM_001321166
Gene Symbol: RICH2
Gene ID (NCBI): 9912
Conjugate: Unconjugated
Form: Liquid
Purification Method: Antigen affinity Purification
UNIPROT ID: Q17R89
Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.
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Collaboration
Tony Tang
Email: Tony.Tang@iright.com
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