Proteintech, 32488-1-AP, KCTD7 Polyclonal antibody

Size: 20ul / 150ul The KCTD7 (32488-1-AP) by Proteintech is a Polyclonal antibody targeting KCTD7 in WB, ELISA applications with reactivity to human samples 32488-1-AP targets KCTD7 in WB, ELISA applications and shows reactivity with human samples. Tested Applications Positive WB detected in: human placenta tissue, human testis tissue Recommended dilution Western Blot (WB): WB : 1:500-1:2000 Background Information KCTD7, or Potassium Channel Tetramerization Domain Containing 7, is a member of the KCTD family of proteins. The role of KCTD7 in regulating autophagy-lysosome pathways, which are essential for cellular homeostasis and response to nutrient stress (PMID: 36964131). It has been implicated in several neurodegenerative disorders, particularly progressive myoclonic epilepsy (PME) and neuronal ceroid lipofuscinosis (NCL). The deficiency of KCTD7 results in the accumulation of lipofuscin and lipid droplets, which are hallmarks of NCL (PMID: 33970744). The 62 kDa form most likely corresponds to an SDS-stable dimer (PMID: 22748208). Specification Tested Reactivity: human Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: CatNo: Ag35756 Product name: Recombinant human KCTD7 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 80-220 aa of NM_153033.4 Sequence: PTDSEGRYFIDRDGTHFGDVLNFLRSGDLPPRERVRAVYKEAQYYAIGPLLEQLENMQPLKGEKVRQAFLGLMPYYKDHLERIVEIARLRAVQRKARFAKLKVCVFKEEMPITPYECPLLNSLRFERSESDGQ Predict reactive species Full Name: potassium channel tetramerisation domain containing 7 Calculated Molecular Weight: 33 kDa，289 aa Observed Molecular Weight: 62 kDa GenBank Accession Number: NM_153033.4 Gene Symbol: KCTD7 Gene ID (NCBI): 154881 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity Purification UNIPROT ID: Q96MP8 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.