Proteintech, 32604-1-AP, CD63 Polyclonal antibody

Size: 20ul / 150ul The CD63 (32604-1-AP) by Proteintech is a Polyclonal antibody targeting CD63 in WB, ELISA applications with reactivity to mouse, rat samples 32604-1-AP targets CD63 in WB, ELISA applications and shows reactivity with mouse, rat samples. Tested Applications Positive WB detected in: mouse brain tissue, mouse kidney tissue, rat brain tissue Recommended dilution Western Blot (WB): WB : 1:500-1:1000 Background Information CD63 is a 30-60 kDa lysosomal membrane protein that belongs to the tetraspanin family. This protein plays many important roles in immunological functions. It mediate signal transduction events that play a role in regulating cell development, activation, and motility. CD63 is expressed on activated platelets, thus it may function as a blood platelet activation marker. CD63 is a lysosomal membrane glycoprotein that is translocated to the plasma membrane after platelet activation. The CD63 tetraspanin is highly expressed in the early stages of melanoma and decreases in advanced lesions, suggesting it as a possible suppressor of tumor progression. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Specification Tested Reactivity: mouse, rat Cited Reactivity: mouse Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: Recombinant protein Predict reactive species Full Name: Cd63 molecule Calculated Molecular Weight: 26 kDa Observed Molecular Weight: 40 kDa GenBank Accession Number: NM_017125.3 Gene Symbol: Cd63 Gene ID (NCBI): 29186 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity Purification UNIPROT ID: P28648 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.