Product Description
Size: 20ul / 150ul
The FAM76B (32882-1-AP) by Proteintech is a Polyclonal antibody targeting FAM76B in WB, ELISA applications with reactivity to human, mouse samples
32882-1-AP targets FAM76B in WB, ELISA applications and shows reactivity with human, mouse samples.
Tested Applications
Positive WB detected in: J774A.1 cells, SH-SY5Y cells, SK-N-SH cells, U-937 cells, RAW 264.7 cells
Recommended dilution
Western Blot (WB): WB : 1:1000-1:8000
Background Information
FAM76B is a nuclear protein with a molecular weight of about 39 kDa. Its amino acid sequence is highly conserved, and it is highly similar to FAM76B sequence of rats, mice and zebrafish. The protein contains histidine repeat sequence (poly-His domain) and ubiquitination site of Lys-225. FAM76B inhibits the inflammatory reaction mediated by NF-κB by affecting the cytoplasmic translocation of hnRNPA2B1. The expression of inflammatory factors (such as IL-6) increased significantly in FAM76B gene knockout mice, indicating that FAM76B has anti-inflammatory effect.
Specification
Tested Reactivity: human, mouse
Host / Isotype: Rabbit / IgG
Class: Polyclonal
Type: Antibody
Immunogen: CatNo: Ag36658 Product name: Recombinant human FAM76B protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 179-277 aa of NM_144664.4 Sequence: HHRHSSSHHKISNLSPEEEQGLWKQSHKSSATIQNETPKKKPKLESKPSNGDSSSINQSADSGGTDNFVLISQLKEEVMSLKRLLQQRDQTILEKDKKL Predict reactive species
Full Name: family with sequence similarity 76, member B
Calculated Molecular Weight: 39kDa,339aa
Observed Molecular Weight: 36-39 kDa
GenBank Accession Number: NM_144664.4
Gene Symbol: FAM76B
Gene ID (NCBI): 143684
Conjugate: Unconjugated
Form: Liquid
Purification Method: Antigen affinity Purification
UNIPROT ID: Q5HYJ3
Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.
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Collaboration
Tony Tang
Email: Tony.Tang@iright.com
Mobile/WhatsApp/Wechat: +86-17717886924