Proteintech, 33057-1-AP, PTCD1 Polyclonal antibody

Size: 20ul / 150ul The PTCD1 (33057-1-AP) by Proteintech is a Polyclonal antibody targeting PTCD1 in WB, ELISA applications with reactivity to human, mouse samples 33057-1-AP targets PTCD1 in WB, ELISA applications and shows reactivity with human, mouse samples. Tested Applications Positive WB detected in: Caco-2 cells, MCF-7 cells, MDA-MB-231 cells, mouse testis tissue Recommended dilution Western Blot (WB): WB : 1:500-1:3000 Background Information PTCD1 protein (Pentatricopeptide Repeat Domain 1) is a nuclear gene-encoded protein located in the mitochondrial matrix. Its core function lies in regulating mitochondrial gene expression and the assembly of the respiratory chain. It specifically recognizes and binds to mitochondrial RNA (such as mRNA or pre-RNA) through its characteristic pentapeptide repeat sequence (PPR) motif, participating in RNA processing, stability maintenance, or translation processes, thereby being crucial for the assembly and function of mitochondrial oxidative phosphorylation complexes (especially complex I). Its deficiency is associated with mitochondrial dysfunction, neurodegenerative diseases, and cardiomyopathy and other pathological processes. Specification Tested Reactivity: human, mouse Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: CatNo: Ag37639 Product name: Recombinant human PTCD1 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 201-595 aa of BC003688 Sequence: VWRLMLSLGLQPSRDSYNLLLVAARDCGLGDPQVASELLLKPREEATVLQPPVSRQRPRRTAQAKAGNLMSAMLHVEALERQLFLEPSQALGPPEPPEARVPGKAQPEVDTKAEPSHTAALTAVALKPPPVELEVNLLTPGAVPPTVVSFGTVTTPADRLALIGGLEGFLSKMAEHRQQPDIRTLTLLAEVVESGSPAESLLLALLDEHQVEADLTFFNTLVRKKSKLGDLEGAKALLPVLAKRGLVPNLQTFCNLAIGCHRPKDGLQLLTDMKKSQVTPNTHIYSALINAAIRKLNYTYLISILKDMKQNRVPVNEVVIRQLEFAAQYPPTFDRYQGKNTYLEKIDGFRAYYKQWLTVMPAEETPHPWQKFRTKPQGDQDTGKEADDGCALGGR Predict reactive species Full Name: pentatricopeptide repeat domain 1 Calculated Molecular Weight: 79 kDa Observed Molecular Weight: 72 kDa GenBank Accession Number: BC003688 Gene Symbol: PTCD1 Gene ID (NCBI): 26024 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity Purification UNIPROT ID: O75127 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.