Proteintech, 33153-1-AP, YM-1+YM-2 Polyclonal antibody

Size: 20ul / 150ul The YM-1+YM-2 (33153-1-AP) by Proteintech is a Polyclonal antibody targeting YM-1+YM-2 in WB, ELISA applications with reactivity to mouse samples 33153-1-AP targets YM-1+YM-2 in WB, ELISA applications and shows reactivity with mouse samples. Tested Applications Positive WB detected in: mouse bone marrow, mouse spleen tissue Recommended dilution Western Blot (WB): WB : 1:5000-1:50000 Background Information Chitinase-like protein 3 (Chil3), also called ECF-L or Ym1, is a member of chitinase-like protein family which has chemotactic activity for eosinophils (PMID: 27256220). CHIL3 promotes NSC self-renewal and commitment to the neuronal lineage. Endogenous expression of CHIL3 is observed in the neurogenic niche of the mouse brain and retina and in lesions of those injury models (PMID: 36368330). Chitinase-like protein 4 (Chil4), also called Ym2, regulates regeneration of the injured OE in vivo in both male and female mice and cell proliferation/differentiation in OE colonies in vitro (PMID: 34016714). This antibody detects both YM1 and YM2. Specification Tested Reactivity: mouse Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: CatNo: Ag39745 Product name: Recombinant mouse CHIL3 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 22-368 aa of NM_009892 Sequence: YQLMCYYTSWAKDRPIEGSFKPGNIDPCLCTHLIYAFAGMQNNEITYTHEQDLRDYEALNGLKDKNTELKTLLAIGGWKFGPAPFSAMVSTPQNRQIFIQSVIRFLRQYNFDGLNLDWQYPGSRGSPPKDKHLFSVLVKEMRKAFEEESVEKDIPRLLLTSTGAGIIDVIKSGYKIPELSQSLDYIQVMTYDLHDPKDGYTGENSPLYKSPYDIGKSADLNVDSIISYWKDHGAASEKLIVGFPAYGHTFILSDPSKTGIGAPTISTGPPGKYTDESGLLAYYEVCTFLNEGATEVWDAPQEVPYAYQGNEWVGYDNVRSFKLKAQWLKDNNLGGAVVWPLDMDDFSGSFCHQRHFPLTSTLKGDLNIHSASCKGPY Predict reactive species Full Name: chitinase 3-like 3 Calculated Molecular Weight: 44 kDa Observed Molecular Weight: 44 kDa GenBank Accession Number: NM_009892 Gene Symbol: Chi3l3 Gene ID (NCBI): 12655 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity Purification UNIPROT ID: O35744 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.