Proteintech, 33274-1-AP, TSPYL6 Polyclonal antibody

Size: 20ul / 150ul The TSPYL6 (33274-1-AP) by Proteintech is a Polyclonal antibody targeting TSPYL6 in WB, ELISA applications with reactivity to human samples 33274-1-AP targets TSPYL6 in WB, ELISA applications and shows reactivity with human samples. Tested Applications Positive WB detected in: K-562 cells Recommended dilution Western Blot (WB): WB : 1:500-1:3000 Background Information TSPYL6 (TSPY-like 6) protein is a member of the TSPY-like nucleoprotein family, and its specific physiological function has not yet been fully elucidated. However, this protein has garnered significant attention in cancer research as "an important tumor biomarker". Studies have shown that TSPYL6 is frequently overexpressed in various malignant tumors, such as breast cancer, lung cancer, colorectal cancer, and hepatocellular carcinoma. Its overexpression promotes tumor cell proliferation, invasion, and metastasis, while inhibiting apoptosis, and is closely associated with poor patient prognosis. Mechanistically, TSPYL6 is believed to exert its cancer-promoting effects by influencing cell cycle progression (e.g., promoting the G1/S phase transition) and regulating key oncogenic signaling pathways such as Wnt/β-catenin. Therefore, TSPYL6 is not only a potential diagnostic and prognostic biomarker but also considered a potential therapeutic target for cancer. Specification Tested Reactivity: human Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: CatNo: Ag38157 Product name: Recombinant human TSPYL6 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-410 aa of BC068576 Sequence: MSLPESPHSPATLDYALEDPHQGQRSREKSKATEVMADMFDGRLEPIVFPPPRLPEEGVAPQDPADGGHTFHILVDAGRSHGAIKAGQEVTPPPAEGLEAASASLTTDSSLKNGFPGEETHGLGGEKALETCGAGRSESEVIAEGKAEDVKPEECAMFSAPVDEKPGGEEMDVAEENRAIDEVNREAGPGPGPGPLNVGLHLNPLESIQLELDSVNAEADRALLQVERRFGQIHEYYLEQRNDIICNIPGFWVTAFRHHPQLSAMIRGQDAEMLSYLTNLEVKELRHPRTGCKFKFFFQRNPYFRNKLIVKVYEVRSFGQVVSFSTLIMWRRGHGPQSFIHRNRHVICSFFTWFSDHSLPESDRIAQIIKEDLWSNPLQYYLLGEDAHRARRRLVREPVEIPRPFGFQCG Predict reactive species Full Name: TSPY-like 6 Calculated Molecular Weight: 410 aa, 46 kDa Observed Molecular Weight: 60 kDa GenBank Accession Number: BC068576 Gene Symbol: TSPYL6 Gene ID (NCBI): 388951 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity Purification UNIPROT ID: Q8N831 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.