Proteintech, 33459-1-AP, IQCG Polyclonal antibody

Size: 20ul / 150ul The IQCG (33459-1-AP) by Proteintech is a Polyclonal antibody targeting IQCG in WB, ELISA applications with reactivity to human, mouse samples 33459-1-AP targets IQCG in WB, ELISA applications and shows reactivity with human, mouse samples. Tested Applications Positive WB detected in: mouse testis tissue Recommended dilution Western Blot (WB): WB : 1:1000-1:4000 Background Information Human IQ motif containing G (IQCG) gene was first reported to be involved in the chromosome translocation in a case of acute T-lymphoid/myeloid leukemia. The expression of Iqcg is prominently enriched in the testis of mice and reveals an ordered expression pattern during spermatogenesis. Iqcg knockout (KO) mice are sterile, due to the severe malformation and total immobility of their spermatozoa. The axoneme in the KO sperm flagellum is disorganized and hardly any typical normal "9+2" pattern, composed of two central microtubules surrounded by nine microtubular doublets, could be found in the KO spermatids. However, the cilia structures in the trachea and oviduct, as well as histological appearances of other major tissues, remain unaffected in the KO mice, suggesting Iqcg's specific role in spermiogenesis (PMID: 24849454). Specification Tested Reactivity: human, mouse Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: CatNo: Ag37506 Product name: Recombinant human IQCG protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 1-372 aa of BC004816 Sequence: TDQLSILNYIMPVQYEGRQSICVKSREMNLEGTNLDKLPMDSTITKIPSPLITEEGPNLPEIRHRGRFAVEFNKMQDLVFKKPTRQTIMTTETLKKIQIDRQFFSHVIADTIKELQDSATYNSLLQALSKERENKMHFYDIIAREEKGRKQIISLQKQLINVKKEWQFEVQSQNEYIANLKDQLQEMKAKSNLENRYMKTNTELQIAQTQKKCNRTEELLVEEIEKLRMKTEEEARTHTEIEMFLRKEQQKLEERLEFWMEKYDKDTEMKQNELNALKATKASDLAHLQDLAKMIREYEQVIIEDRIEKERSKKKVKQDLLELKSVIKLQAWWRGTMIRREIGGFKMPKDKVDSKDSKGKGKGKDKRRGKKK Predict reactive species Full Name: IQ motif containing G Calculated Molecular Weight: 51 kDa Observed Molecular Weight: 50 kDa GenBank Accession Number: BC004816 Gene Symbol: IQCG Gene ID (NCBI): 84223 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity Purification UNIPROT ID: Q9H095 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.