Proteintech, 33569-1-AP, CCDC88A Polyclonal antibody

Size: 20ul / 150ul The CCDC88A (33569-1-AP) by Proteintech is a Polyclonal antibody targeting CCDC88A in WB, ELISA applications with reactivity to human samples 33569-1-AP targets CCDC88A in WB, ELISA applications and shows reactivity with human samples. Tested Applications Positive WB detected in: A431 cells Recommended dilution Western Blot (WB): WB : 1:500-1:2000 Background Information CCDC88A, also named as APE, GRDN and KIAA1212, belongs to the CCDC88 family. CCDC88A enhances phosphoinositide 3-kinase (PI3K)-dependent phosphorylation and kinase activity of AKT1/PKB, but does not possess kinase activity itself. Phosphorylation of AKT1/PKB thereby it induces the phosphorylation of downstream effectors GSK3 and FOXO1/FKHR, and regulates DNA replication and cell proliferation CCDC88A is essential for the integrity of the actin cytoskeleton and for cell migration. It is required for formation of actin stress fibers and lamellipodia. It may be involved in membrane sorting in the early endosome. Specification Tested Reactivity: human Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: CatNo: Ag37983 Product name: Recombinant human CCDC88A protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1500-1843 aa of BC132736 Sequence: GAMAFSTTAINFSTVNSSAGFRSKQLVNNKDTTSFEDISPQGVSDDSSTGSRVHASRPASLDSGRTSTSNSNNNASLHEVKAGAVNNQSRPQSHSSGEFSLLHDHEAWSSSGSSPIQYLKRQTRSSPVLQHKISETLESRHHKIKTGSPGSEVVTLQQFLEESNKLTSVQIKSSSQENLLDEVMKSLSVSSDFLGKDKPVSCGLARSVSGKTPGDFYDRRTTKPEFLRPGPRKTEDTYFISSAGKPTPGTQGKIKLVKESSLSRQSKDSNPYATLPRASSVISTAEGTTRRTSIHDFLTKDSRLPISVDSPPAAADSNTTAASNVDKVQESRNSKSRSREQQSS Predict reactive species Full Name: coiled-coil domain containing 88A Observed Molecular Weight: 220 kDa GenBank Accession Number: BC132736 Gene Symbol: CCDC88A Gene ID (NCBI): 55704 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity Purification UNIPROT ID: Q3V6T2 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.