Product Description
Size: 20ul / 150ul
The C10orf76 (33627-1-AP) by Proteintech is a Polyclonal antibody targeting C10orf76 in WB, ELISA applications with reactivity to human samples
33627-1-AP targets C10orf76 in WB, ELISA applications and shows reactivity with human samples.
Tested Applications
Positive WB detected in: HeLa cells, MCF-7 cells
Recommended dilution
Western Blot (WB): WB : 1:500-1:1000
Background Information
C10orf76, also known as ARMH3 (Armadillo-like helical domain-containing protein 3), was previously reported to be a regulator of phosphatidylinositol 4-kinase beta (PI4KB, also known as PI4KIIIbeta) at the TGN. Upon cGAMP-triggered translocation, ARMH3 interacted with STING at the Golgi and recruited phosphatidylinositol 4-kinase beta (PI4KB) to synthesize PI4P, which directed STING Golgi-to-endosome trafficking via PI4P-binding proteins AP-1 and GGA2 (PMID: 39580461, 36921576).
Specification
Tested Reactivity: human
Host / Isotype: Rabbit / IgG
Class: Polyclonal
Type: Antibody
Immunogen: CatNo: Ag38164 Product name: Recombinant human C10orf76 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 539-689 aa of NM_024541.2 Sequence: DTFLPTPSSYDELYYEIIRMHQSFDNLYSMVLRLSTNAGQWKEAASKVTHALVNIRAIINHFNPKIESYAAVNHISQLSEEQVLEVVRANYDTLTLKLQDGLDQYERYSEQHKEAAFFKELVRSISTNVRRNLAFHTLSQEVLLKEFSTIS Predict reactive species
Full Name: chromosome 10 open reading frame 76
Calculated Molecular Weight: 79kDa,689aa
Observed Molecular Weight: 70-79 kDa
GenBank Accession Number: NM_024541.2
Gene Symbol: C10orf76
Gene ID (NCBI): 79591
Conjugate: Unconjugated
Form: Liquid
Purification Method: Antigen affinity Purification
UNIPROT ID: Q5T2E6
Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.
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Collaboration
Tony Tang
Email: Tony.Tang@iright.com
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