Proteintech, 33876-1-AP, GGT1 Polyclonal antibody

Size: 20ul / 150ul The GGT1 (33876-1-AP) by Proteintech is a Polyclonal antibody targeting GGT1 in WB, ELISA applications with reactivity to mouse, rat samples 33876-1-AP targets GGT1 in WB, ELISA applications and shows reactivity with mouse, rat samples. Tested Applications Positive WB detected in: mouse kidney tissue, rat kidney tissue Recommended dilution Western Blot (WB): WB : 1:1000-1:6000 Background Information GGT1 is a heterodimer composed of light chain and heavy chain, and its active site is located in the light chain. The metabolism of glutathione by GGT1 releases free glutamic acid and dipeptide cysteine-glycine, which can be hydrolyzed into cysteine and glycine by dipeptidase. In the presence of high concentration of dipeptide and some amino acids, it can also catalyze the peptide transfer reaction and transfer γ -glutamyl group to receptor amino acids to form new γ -glutamyl compounds. Participate in cysteine homeostasis, glutathione homeostasis and the transformation of leukotriene LTC4 to LTD4 (PMID:12810527). Specification Tested Reactivity: mouse, rat Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: CatNo: Eg6301 Product name: Recombinant mouse CD224/GGT1 protein Source: mammalian cells -derived, V37 Tag: C-rFc Domain: 27-568 aa of NM_001305992.1 Sequence: PYTSGKPDHVYSRAAVATDAKRCSEIGRDILQEGGSVVDAAIASLLCMGLMNAHSMGIGGGLFFTIYNSTTGKVEVINAREVAPRLANTTMFNNSKDSEEGGLSVAVPGEIRGYELAHQRHGRLPWARLFQPSIQLARHGFPVGKGLAIALDKKRDVIEKTPALCEVFCRQGKVLQEGETVTMPKLADTLQILAQEGAKAFYNGSLTAQIVKDIQEAGGIMTVEDLNNYRAELIEHPMSIGLGDATLYVPSAPLSGPVLILILNILKGYNFSPKSVATPEQKALTYHRIVEAFRFAYAKRTMLGDPKFVDVSQVIRNMSSEFYATQLRARITDETTHPAAYYEPEFYLQDDGGTAHLSAVSEDGSAVAATSTINLYFGSKVLSRVSGILFNDEMDDFSSPNFINQFRVAPSPANFIKPGKQPLSSMCPSIILDKDGQVRMVVGASGGTQITTSVALAIINSLWFGYDVKRAVEEPRLHNQLLPNTTTVEKDIDQVVTAGLKIRHHHTEVTPTFIAVVQAVVRASGGWAAASDSRKGGEPAGY Predict reactive species Full Name: gamma-glutamyltransferase 1 Calculated Molecular Weight: 62 kDa Observed Molecular Weight: 50-61 kDa GenBank Accession Number: NM_001305992.1 Gene Symbol: Ggt1 Gene ID (NCBI): 14598 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity Purification UNIPROT ID: Q60928 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.