Proteintech, 51004-1-AP, GEFT Polyclonal antibody

Size: 20ul / 150ul The GEFT (51004-1-AP) by Proteintech is a Polyclonal antibody targeting GEFT in WB, ELISA applications with reactivity to human, mouse, rat samples 51004-1-AP targets GEFT in WB, ELISA applications and shows reactivity with human, mouse, rat samples. Tested Applications Positive WB detected in: mouse brain tissue, rat brain tissues Recommended dilution Western Blot (WB): WB : 1:500-1:1000 Background Information GEFT, also named as p63RhoGEF, may play a role in actin cytoskeleton reorganization in different tissues since its activation induces formation of actin stress fibers. It works as a guanine nucleotide exchange factor for Rho family of small GTPases. GETF links specifically G alpha q/11-coupled receptors to RHOA activation. GEFT may be an important regulator of processes involved in axon and dendrite formation. In neurons seems to be an exchange factor primarily for RAC1. It is involved in skeletal myogenesis. GEFT is expressed as three isoforms (64, 53 and 68kDa). Specification Tested Reactivity: human, mouse, rat Cited Reactivity: human, mouse, rat Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: Peptide Predict reactive species Full Name: RhoA/RAC/CDC42 exchange factor Calculated Molecular Weight: 64 kDa Observed Molecular Weight: 70 kDa GenBank Accession Number: BC047559 Gene Symbol: GEFT Gene ID (NCBI): 115557 RRID: AB_2089321 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity purification UNIPROT ID: Q86VW2 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.