Proteintech, 55068-1-AP, Integrin alpha-8 Polyclonal antibody

Size: 20ul / 150ul The Integrin alpha-8 (55068-1-AP) by Proteintech is a Polyclonal antibody targeting Integrin alpha-8 in WB, ELISA applications with reactivity to human, mouse samples 55068-1-AP targets Integrin alpha-8 in WB, ELISA applications and shows reactivity with human, mouse samples. Tested Applications Positive WB detected in: mouse lung tissue Recommended dilution Western Blot (WB): WB : 1:500-1:1000 Background Information Integrins are cell adhesion receptors that are heterodimers composed of non-covalently associated α and β subunits. Integrin alpha-8 is a single-pass type I membrane protein that forms a heterodimer with integrin beta-1 to serve as a receptor for RGD-containing matrix molecules (fibronectin, vitronectin, tenascin C, osteopontin, and nephronectin) (PMID: 33000355). Integrin alpha-8 beta-1 plays a critical role in epithelial-mesenchymal interactions and functions in the genesis of kidney and probably of other organs (PMID: 9054500; 19769957). The apparent molecular weight of integrin alpha-8 is larger than the calculated molecular weight of 117 kDa, possibly due to glycosylation (PMID: 7768999). Specification Tested Reactivity: human, mouse Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: Peptide Predict reactive species Full Name: integrin, alpha 8 Calculated Molecular Weight: 117 kDa Observed Molecular Weight: 140 kDa GenBank Accession Number: NM_003638 Gene Symbol: Integrin alpha 8 Gene ID (NCBI): 8516 RRID: AB_3086432 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity purification UNIPROT ID: P53708 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.