Proteintech, 55224-1-AP, HCN4 Polyclonal antibody

Size: 20ul / 150ul The HCN4 (55224-1-AP) by Proteintech is a Polyclonal antibody targeting HCN4 in WB, ELISA applications with reactivity to human, mouse, rat samples 55224-1-AP targets HCN4 in WB, ELISA applications and shows reactivity with human, mouse, rat samples. Tested Applications Positive WB detected in: mouse brain tissue, rat brain tissue Recommended dilution Western Blot (WB): WB : 1:1000-1:8000 Background Information HCN4 belongs to the potassium channel HCN family. It hyperpolarization-activated ion channel with very slow activation and inactivation exhibiting weak selectivity for potassium over sodium ions. HCN4 may contribute to the native pacemaker currents in heart (If) and in neurons (Ih). It is activated by cAMP. HCN4 may mediate responses to sour stimuli. (PMID:10228147). Defects in HCN4 are a cause of sick sinus syndrome type 2 (SSS2). Defects in HCN4 are the cause of Brugada syndrome type 8 (BRS8). This antibody is specific to HCN4. Specification Tested Reactivity: human, mouse, rat Cited Reactivity: human, mouse, rat, hamster Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: Peptide Predict reactive species Full Name: hyperpolarization activated cyclic nucleotide-gated potassium channel 4 Calculated Molecular Weight: 129 kDa Observed Molecular Weight: 140-160 kDa GenBank Accession Number: NM_005477 Gene Symbol: HCN4 Gene ID (NCBI): 10021 RRID: AB_11182714 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity purification UNIPROT ID: Q9Y3Q4 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.