Proteintech, 60179-1-Ig, CD109 Monoclonal antibody

Size: 20ul / 150ul The CD109 (60179-1-Ig) by Proteintech is a Monoclonal antibody targeting CD109 in WB, ELISA applications with reactivity to human samples 60179-1-Ig targets CD109 in WB, IHC, ELISA applications and shows reactivity with human samples. Tested Applications Positive WB detected in: Jurkat cells Recommended dilution Western Blot (WB): WB : 1:1000-1:8000 Background Information CD109, also named as CPAMD7, is a member of the alpha2-macroglobulin/complement superfamily. It is a glycosylphosphatidylinositol (GPI)-linked cell surface glycoprotein of approximately 170kd which is found on the cell surface of platelets, activated T-cells, and endothelial cells. CD109 binds to and negatively regulates signaling of transforming growth factor beta (TGF-beta). CD109 has been identified as part of the TGF-beta receptor system in human keratinocytes. Up regulation of CD109 expression has been observed in several different types of tumor.CD109 is a glycosyl-phosphatidylinositol-anchored glycoprotein that is a member of the a2-macroglobulin/C3, C4, C5 family of thioester-containing proteins. There're 2 forms of 150 (p150) and 120 kDa (p120) exist due to proteolytic degradation from a 180 kDa form. The antibody can recognize all these 4 isoforms. Specification Tested Reactivity: human Cited Reactivity: human, rat Host / Isotype: Mouse / IgG1 Class: Monoclonal Type: Antibody Immunogen: Peptide Predict reactive species Full Name: CD109 molecule Calculated Molecular Weight: 162 kDa Observed Molecular Weight: 162 kDa GenBank Accession Number: BC152996 Gene Symbol: CD109 Gene ID (NCBI): 135228 RRID: AB_10892668 Conjugate: Unconjugated Form: Liquid Purification Method: Protein G purification UNIPROT ID: Q6YHK3 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.