Proteintech, 60262-1-Ig, IL-1R2 Monoclonal antibody

Size: 20ul / 150ul The IL-1R2 (60262-1-Ig) by Proteintech is a Monoclonal antibody targeting IL-1R2 in WB, IF/ICC, ELISA applications with reactivity to human, mouse samples 60262-1-Ig targets IL-1R2 in WB, IF/ICC, ELISA applications and shows reactivity with human, mouse samples. Tested Applications Positive WB detected in: HeLa cells Positive IF/ICC detected in: Jurkat cells Recommended dilution Western Blot (WB): WB : 1:500-1:2000 Immunofluorescence (IF)/ICC: IF/ICC : 1:200-1:800 Background Information Interleukin-1 receptor type 2 (IL1R2, also known as CD121b) is a cytokine receptor that belongs to the interleukin 1 receptor family. It exists in both a membrane bound and soluble form. IL1R2 binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. IL1R2 serves as a negative regulator of IL-1 signaling, thereby suppressing inflammatory response. Specification Tested Reactivity: human, mouse Cited Reactivity: human, mouse, rat Host / Isotype: Mouse / IgG2a Class: Monoclonal Type: Antibody Immunogen: CatNo: Ag4495 Product name: Recombinant human IL-1R2 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 24-347 aa of BC039031 Sequence: AARSCRFRGRHYKREFRLEGEPVALRCPQVPYWLWASVSPRINLTWHKNDSARTVPGEEETRMWAQDGALWLLPALQEDSGTYVCTTRNASYCDKMSIELRVFENTDAFLPFISYPQILTLSTSGVLVCPDLSEFTRDKTDVKIQWYKDSLLLDKDNEKFLSVRGTTHLLVHDVALEDAGYYRCVLTFAHEGQQYNITRSIELRIKKKKEETIPVIISPLKTISASLGSRLTIPCKVFLGTGTPLTTMLWWTANDTHIESAYPGGRVTEGPRQEYSENNENYIEVPLIFDPVTREDLHMDFKCVVHNTLSFQTLRTTVKEASST Predict reactive species Full Name: interleukin 1 receptor, type II Calculated Molecular Weight: 398 aa, 45 kDa Observed Molecular Weight: 45 kDa GenBank Accession Number: BC039031 Gene Symbol: IL1R2 Gene ID (NCBI): 7850 RRID: AB_2881383 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: P27930 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.