Proteintech, 65186-1-Ig, Anti-Human CD13 (WM15)

Size: 100ug / 500ug The CD13 (65186-1-Ig) by Proteintech is a Monoclonal antibody targeting CD13 in IF/ICC, FC applications with reactivity to human, non-human primates samples 65186-1-Ig targets CD13 in IF/ICC, FC applications and shows reactivity with human, non-human primates samples. Tested Applications Positive IF/ICC detected in: HUVEC cells, THP-1 cells Positive FC detected in: human PBMCs Recommended dilution Immunofluorescence (IF)/ICC: IF/ICC : 1:500-1:2000 Flow Cytometry (FC): FC : 0.2 ug per 10^6 cells in 100 μl suspension Background Information CD13, also named as APN, ANPEP (aminopeptidase N) or PEPN, is belongs to the peptidase M1 family. CD13 is a heavily glycosylated, ~150-240 kDa, type-II membrane, expressed by most cells of myeloid origin including monocytes, macrophages, granulocytes, and their hematopoietic precursors. It is also abundantly expressed in the brush border of epithelial cells from renal proximal tubules and small intestine, in prostatic epithelial cells, in bile duct canaliculi, in mast cells, and, in some cases, in fibroblasts and smooth muscle cells. CD13 is a multifunctional protein and plays varying roles in cell migration, cell proliferation, cell differentiation and so on. CD13 participates in angiogenesis generating and modulating angiogenic signals, and can be a marker of angiogenic vessels. CD13 is also a pan-myeloid marker, present on mature granulocytes and monocytes. (PMID: 8805662, 10098327, 18603472, 18097955, 17897790, 17888402, 21339174) Specification Tested Reactivity: human, non-human primates Host / Isotype: Mouse / IgG1, kappa Class: Monoclonal Type: Antibody Immunogen: Human AML cells Predict reactive species Full Name: alanyl (membrane) aminopeptidase Calculated Molecular Weight: 110 kDa GenBank Accession Number: BC058928 Gene Symbol: CD13 Gene ID (NCBI): 290 ENSEMBL Gene ID: ENSG00000166825 RRID: AB_2918457 Conjugate: Unconjugated Form: Liquid Purification Method: Protein G purification UNIPROT ID: P15144 Storage Buffer: PBS with 0.09% sodium azide, pH 7.3. Storage Conditions: Store at 2-8°C. Stable for one year after shipment.