Proteintech, 65190-1-Ig, Anti-Human CD18 (TS1/18)

Size: 100ug / 500ug The CD18 (65190-1-Ig) by Proteintech is a Monoclonal antibody targeting CD18 in FC applications with reactivity to human samples 65190-1-Ig targets CD18 in FC applications and shows reactivity with human samples. Tested Applications Positive FC detected in: human PBMCs Recommended dilution Flow Cytometry (FC): FC : 0.2 ug per 10^6 cells in 100 μl suspension Background Information CD18, also known as integrin beta-2, is a transmembrane protein that forms heterodimers with CD11a, CD11b, CD11c, CD11d (PMID: 1968349). CD11a/CD18 (LFA-1) is expressed by all leukocytes, while CD11b/CD18 (Mac-1) and CD11c/CD18 (p150,95) are normally restricted to expression on monocytes, macrophages, polymorphonuclear lymphocytes (PMNs), and natural killer cells (PMID: 1968349; 3109455; 10946284). CD18 plays an important role in mediating cell adhesion during immune response and defects of CD18 cause leukocyte adhesion deficiency (PMID: 3594570). Specification Tested Reactivity: human Host / Isotype: Mouse / IgG1, kappa Class: Monoclonal Type: Antibody Immunogen: Human Beta 2 Integrin Predict reactive species Full Name: integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) Calculated Molecular Weight: 85 kDa GenBank Accession Number: BC005861 Gene Symbol: CD18 Gene ID (NCBI): 3689 ENSEMBL Gene ID: ENSG00000160255 RRID: AB_2918460 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: P05107 Storage Buffer: PBS with 0.09% sodium azide, pH 7.3. Storage Conditions: Store at 2-8°C. Stable for one year after shipment.