Proteintech, 65223-1-Ig, Anti-Human ALCAM (3A6)

Size: 100ug / 500ug The ALCAM (65223-1-Ig) by Proteintech is a Monoclonal antibody targeting ALCAM in FC applications with reactivity to Human samples 65223-1-Ig targets ALCAM in FC applications and shows reactivity with Human samples. Tested Applications Positive FC detected in: PHA treated human PBMCs Recommended dilution Flow Cytometry (FC): FC : 0.2 ug per 10^6 cells in 100 μl suspension Background Information Activated leukocyte cell adhesion molecule (ALCAM, also known as CD166) is a cell adhesion molecule that belongs to the immunoglobulin superfamily. It is involved in cell-cell adhesion through homophilic and heterophilic (to CD6) interactions. ALCAM is widely expressed in a variety of normal tissues and cell types, including activated T cells and monocytes, epithelial cells, fibroblasts, neuronal cells, hepatocytes, and bone marrow mesenchymal stem cells (PMID: 7760007; 25221999). Altered ALCAM expression has been associated with the differentiation state and progression in some neoplasms including melanoma, prostate, colorectal, and breast cancers (PMID: 20461761; 18172759). Specification Tested Reactivity: Human Host / Isotype: Mouse / IgG1, kappa Class: Monoclonal Type: Antibody Immunogen: Cultured human thymic epithelial cells Predict reactive species Full Name: activated leukocyte cell adhesion molecule Calculated Molecular Weight: 105 kDa GenBank Accession Number: BC057809 Gene Symbol: ALCAM Gene ID (NCBI): 214 RRID: AB_2935133 Conjugate: Unconjugated Form: Liquid Purification Method: Protein G purification UNIPROT ID: Q13740 Storage Buffer: PBS with 0.09% sodium azide, pH 7.3. Storage Conditions: Store at 2-8°C. Stable for one year after shipment.