Proteintech, 65230-1-Ig, Anti-Mouse CD200 (OX90)

Size: 100ug / 500ug The CD200 (65230-1-Ig) by Proteintech is a Monoclonal antibody targeting CD200 in FC applications with reactivity to Mouse samples 65230-1-Ig targets CD200 in FC applications and shows reactivity with Mouse samples. Tested Applications Positive FC detected in: mouse splenocytes Recommended dilution Flow Cytometry (FC): FC : 1 ug per 10^6 cells in 100 μl suspension Background Information CD200, also known as OX2, is a type I transmembrane glycoprotein that belongs to the immunoglobulin superfamily (PMID: 3032785). It contains two extracellular immunoglobulin domains, a transmembrane and a cytoplasmic domain. CD200 is expressed on a variety of cell types, including thymocytes, B lymphocytes, a subset of T lymphocytes, follicular dendritic cells, neurons, and endothelial cells (PMID: 3032785; 10981966). CD200 binds to its receptor, CD200R, which is primarily expressed by myeloid and T cell lineage (PMID: 15187158). The CD200-CD200R interaction plays a role in immunosuppression and suppression of anti-tumor immune responses (PMID: 22020332). Specification Tested Reactivity: Mouse Host / Isotype: Rat / IgG2a, kappa Class: Monoclonal Type: Antibody Immunogen: Mouse CD200-rat CD4 fusion protein Predict reactive species Full Name: CD200 antigen GenBank Accession Number: BC051984 Gene Symbol: Cd200 Gene ID (NCBI): 17470 RRID: AB_3670279 Conjugate: Unconjugated Form: Liquid Purification Method: Affinity purification UNIPROT ID: Q80VX2 Storage Buffer: PBS with 0.09% sodium azide, pH 7.3. Storage Conditions: Store at 2-8°C. Stable for one year after shipment.