Proteintech, 65234-1-Ig, Anti-Rat CD45RA (OX-33)

Size: 100ug / 500ug The CD45RA (65234-1-Ig) by Proteintech is a Monoclonal antibody targeting CD45RA in FC applications with reactivity to rat samples 65234-1-Ig targets CD45RA in FC applications and shows reactivity with rat samples. Tested Applications Positive FC detected in: Wistar rat splenocytes Recommended dilution Flow Cytometry (FC): FC : 0.5 ug per 10^6 cells in 100 μl suspension Background Information CD45, also known as protein tyrosine phosphatase, receptor type C, is a type I transmembrane protein expressed on the surface of all haematopoietic cells with the exception of erythrocytes and platelets (PMID: 3489673; 28615666). CD45 is a pan-haematopoietic cell marker and has been shown to be essential for T- and B-cell activation and signalling (PMID: 9429890; 16378097). CD45 exists as multiple isoforms due to alternative splicing of three exons (4, 5, and 6, designated A, B, and C) in the extracellular domain (PMID: 12414720). CD45RA is expressed on naïve T cells, B cells, and monocytes (PMID: 1830500; 14687231). Specification Tested Reactivity: rat Host / Isotype: Mouse / IgG1, kappa Class: Monoclonal Type: Antibody Immunogen: Leukocyte common antigen purified from rat splenocytes Predict reactive species Full Name: protein tyrosine phosphatase, receptor type, C Calculated Molecular Weight: 143 kDa GenBank Accession Number: XM_006249910 Gene Symbol: CD45 Gene ID (NCBI): 24699 RRID: AB_2935147 Conjugate: Unconjugated Form: Liquid Purification Method: Affinity purification UNIPROT ID: P04157 Storage Buffer: PBS with 0.09% sodium azide, pH 7.3. Storage Conditions: Store at 2-8°C. Stable for one year after shipment.