Proteintech, 65290-1-Ig, Anti-Mouse CD19 (1D3)

Size: 100ug / 500ug The CD19 (65290-1-Ig) by Proteintech is a Monoclonal antibody targeting CD19 in IF-Fro, FC applications with reactivity to mouse samples 65290-1-Ig targets CD19 in IF-Fro, FC applications and shows reactivity with mouse samples. Tested Applications Positive IF-Fro detected in: mouse spleen tissue Positive FC detected in: mouse splenocytes Recommended dilution Immunofluorescence (IF)-FRO: IF-FRO : 1:200-1:800 Flow Cytometry (FC): FC : 0.5 ug per 10^6 cells in 100 μl suspension Background Information CD19 is a 95 kDa type I transmembrane glycoprotein belonging to the immunoglobulin superfamily (PMID: 2472450). It is expressed by B cells and follicular dendritic cells. CD19 is up-regulated at the step of B-lineage commitment during the differentiation of the hematopoietic stem cell, it remains on during subsequent stages of differentiation until finally down-regulated during terminal differentiation into plasma cells (PMID: 8528044). CD19 is involved in B cell development, activation and differentiation. It is the dominant component for the signaling complex on B cells that includes CD21 (CR2), CD81 (TAPA-1) and CD225 and acts as a critical co-receptor for BCR signal transduction (PMID: 23210908). Specification Tested Reactivity: mouse Host / Isotype: Rat / IgG2a, kappa Class: Monoclonal Type: Antibody Immunogen: Mouse CD19 Transfected Cell Line Predict reactive species Full Name: CD19 antigen GenBank Accession Number: BC156767 Gene Symbol: Cd19 Gene ID (NCBI): 12478 RRID: AB_3084916 Conjugate: Unconjugated Form: Liquid Purification Method: Affinity purification UNIPROT ID: P25918 Storage Buffer: PBS with 0.09% sodium azide, pH 7.3. Storage Conditions: Store at 2-8°C. Stable for one year after shipment.