Proteintech, 65602-2-AR, Anti-Mouse CD11c (N418) Armenian Hamster Recombinant Antibody

Size: 100ug The CD11c (65602-2-AR) by Proteintech is a Recombinant antibody targeting CD11c in FC applications with reactivity to mouse samples 65602-2-AR targets CD11c in FC applications and shows reactivity with mouse samples. Tested Applications Positive FC detected in: mouse splenocytes Recommended dilution Flow Cytometry (FC): FC : 0.5 ug per 10^6 cells in a 100 µl suspension Background Information Integrins are cell adhesion receptors that are heterodimers composed of non-covalently associated α and β subunits (PMID: 9779984). CD11c, also known as integrin αX, is a type I transmembrane glycoprotein present on a variety of cells, including monocytes/macrophages, granulocytes, a subset of B cells, NK cells and dendritic cells (PMID: 2897326; 1680915; 1694698; 17389580). As a result of its high level of expression on most dendritic cells, CD11c is typically considered to be a marker of conventional dendritic cells (PMID: 27119555). CD11c forms an α/β heterodimer with CD18 (integrin β2). CD11c/CD18 acts a receptor for fibrinogen and is important in monocyte adhesion and chemotaxis (PMID: 1671533). Specification Tested Reactivity: mouse Host / Isotype: Armenian Hamster / IgG2a Class: Recombinant Type: Antibody Immunogen: N/A Predict reactive species Full Name: integrin alpha X GenBank Accession Number: BC167225 Gene Symbol: CD11c Gene ID (NCBI): 16411 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification Storage Buffer: PBS with 0.09% sodium azide, pH 7.3. Storage Conditions: Store at 2-8°C. Stable for one year after shipment.