Proteintech, 66137-1-Ig, IFITM2-Specific Monoclonal antibody

Size: 20ul / 150ul The IFITM2-Specific (66137-1-Ig) by Proteintech is a Monoclonal antibody targeting IFITM2-Specific in WB, ELISA applications with reactivity to human samples 66137-1-Ig targets IFITM2-Specific in WB, IHC, IF, ELISA applications and shows reactivity with human samples. Tested Applications Positive WB detected in: HepG2 cells, recombinant protein Recommended dilution Western Blot (WB): WB : 1:500-1:2000 Background Information IFITM2, also named as 1-8D, belongs to the CD225 family. It is an IFN-induced antiviral protein that mediates cellular innate immunity to at least three major human pathogens, namely influenza A H1N1 virus, West Nile virus (WNV), and dengue virus (WNV), by inhibiting the early step(s) of replication. IFITM2 induces cell cycle arrest and mediates apoptosis by caspase activation and in p53-independent manner. It is overexpressed in colon carcinoma. IFITM2 is a novel pro-apoptotic gene that will provide new insights into the regulated cellular pathways to death.(PMID:19544527) This antibody is specific to IFTIM2. Specification Tested Reactivity: human Cited Reactivity: human Host / Isotype: Mouse / IgG1 Class: Monoclonal Type: Antibody Immunogen: Recombinant protein Predict reactive species Full Name: interferon induced transmembrane protein 2 (1-8D) Observed Molecular Weight: 15 kDa GenBank Accession Number: NM_006435 Gene Symbol: IFITM2 Gene ID (NCBI): 10581 RRID: AB_2881536 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: Q01629 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.