Product Description
Size: 20ul / 150ul
The NRG1, isoform SMDF (66492-1-Ig) by Proteintech is a Monoclonal antibody targeting NRG1, isoform SMDF in WB, IF/ICC, ELISA applications with reactivity to human, mouse, rat, pig, rabbit samples
66492-1-Ig targets NRG1, isoform SMDF in WB, IHC, IF/ICC, ELISA applications and shows reactivity with human, mouse, rat, pig, rabbit samples.
Tested Applications
Positive WB detected in: rat brain tissue, HepG2 cells, pig cerebellum tissue, rat cerebellum tissue, mouse cerebellum tissue, mouse brain tissue, rabbit brain tissue
Positive IF/ICC detected in: MCF-7 cells
Recommended dilution
Western Blot (WB): WB : 1:5000-1:50000
Immunofluorescence (IF)/ICC: IF/ICC : 1:200-1:800
Background Information
Neuregulin 1 (NRG1) is a trophic factor that has been implicated in neural development, neurotransmission, and synaptic plasticity. NRG1 has multiple isoforms that are generated by usage of different promoters and alternative splicing of a single gene. NRG1 and its receptor ErbB tyrosine kinase are expressed not only in the developing nervous system, but also in the adult brain. The antibody is specific to NRG1 isoform SMDF.
Specification
Tested Reactivity: human, mouse, rat, pig, rabbit
Cited Reactivity: mouse, rat
Host / Isotype: Mouse / IgG1
Class: Monoclonal
Type: Antibody
Immunogen: CatNo: Ag0803 Product name: Recombinant human NRG1 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-225 aa of BC007675 Sequence: MEIYSPDMSEVAAERSSSPSTQLSADPSLDGLPAAEDMPEPQTEDGRTPGLVGLAVPCCACLEAERLRGCLNSEKICIVPILACLVSLCLCIAGLKWVFVDKIFEYDSPTHLDPGGLGQDPIISLDATAASALWVSSEAYTSPVSRAQSESEVQVTVQGDKAVVSFEPSAAPTPKNRIFAFSFLPSTAPSFPSPTRNPEVRTPKSATQPQTTETNLQTAPKLSTS Predict reactive species
Full Name: neuregulin 1
Calculated Molecular Weight: 70 kDa
Observed Molecular Weight: 70 kDa
GenBank Accession Number: BC007675
Gene Symbol: NRG1
Gene ID (NCBI): 3084
RRID: AB_2881857
Conjugate: Unconjugated
Form: Liquid
Purification Method: Protein G purification
UNIPROT ID: Q02297
Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.
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Collaboration
Tony Tang
Email: Tony.Tang@iright.com
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