Proteintech, 66513-1-Ig, OLIG2 (for WB only) Monoclonal antibody

Size: 20ul / 150ul The OLIG2 (for WB only) (66513-1-Ig) by Proteintech is a Monoclonal antibody targeting OLIG2 (for WB only) in WB, ELISA applications with reactivity to human samples 66513-1-Ig targets OLIG2 (for WB only) in WB, ELISA applications and shows reactivity with human samples. Tested Applications Positive WB detected in: human brain tissue, human cerebellum tissue Recommended dilution Western Blot (WB): WB : 1:1000-1:6000 Background Information OLIG2, also named as BHLHB1, BHLHE19, PRKCBP2 and RACK17, is required for oligodendrocyte and motor neuron specification in the spinal cord, as well as for the development of somatic motor neurons in the hindbrain. Cooperates with OLIG1, OLIG2 establish the pMN domain of the embryonic neural tube. Antagonist of V2 interneuron and of NKX2-2-induced V3 interneuron development. OLIG2 is widely expressed in subsets of glia cells and progenitors, and it is strongly induced at different sites by both acute and chronic injury, albeit with different mechanisms. OLIG2 acts as a repressor of neurogenesis in cells reacting to brain injury. It may represent an effective approach towards evoking neuronal repair from parenchymal precursors.(PMID:19390819 ) Specification Tested Reactivity: human Cited Reactivity: human Host / Isotype: Mouse / IgG2a Class: Monoclonal Type: Antibody Immunogen: CatNo: Ag18838 Product name: Recombinant human OLIG2 protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 1-323 aa of BC047511 Sequence: MDSDASLVSSRPSSPEPDDLFLPARSKGSSGSAFTGGTVSSSTPSDCPPELSAELRGAMGSAGAHPGDKLGGSGFKSSSSSTSSSTSSAAASSTKKDKKQMTEPELQQLRLKINSRERKRMHDLNIAMDGLREVMPYAHGPSVRKLSKITTLLLARNYILMLTNSLEEMKRLVSEIYGGHHAGFHPSACGGLAHSAPLPAATAHPAAAAHAAHHPAVHHPILPPAAAAAAAAAAAAAVSSASLPGSGLPSVGSIRPPHGLLKSPSAAAAAPLGGGGGGSGASGGFQHWGGMPCPCSMCQVPPPHHHVSAMGAGSLPRLTSDAK Predict reactive species Full Name: oligodendrocyte lineage transcription factor 2 Calculated Molecular Weight: 32 kDa Observed Molecular Weight: 35-39 kDa GenBank Accession Number: BC047511 Gene Symbol: OLIG2 Gene ID (NCBI): 10215 RRID: AB_2881876 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: Q13516 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.