Product Description
Size: 20ul / 150ul
The KAT2A/GCN5 (66575-1-Ig) by Proteintech is a Monoclonal antibody targeting KAT2A/GCN5 in WB, IF/ICC, ELISA applications with reactivity to Human, mouse, rat samples
66575-1-Ig targets KAT2A/GCN5 in WB, IHC, IF/ICC, IP, CoIP, ELISA applications and shows reactivity with Human, mouse, rat samples.
Tested Applications
Positive WB detected in: HeLa cells, MCF-7 cells, HSC-T6 cells, NIH/3T3 cells, SKOV-3 cells
Positive IF/ICC detected in: SKOV-3 cells
Recommended dilution
Western Blot (WB): WB : 1:2000-1:10000
Immunofluorescence (IF)/ICC: IF/ICC : 1:200-1:800
Background Information
GCN5, encoded by KAT2A, is a member of nuclear A-type histone acetyltransferase (HAT) which has direct impact on gene transcription. Additionally, GCN5 has roles in cell cycle regulation, DNA replication, and DNA repair, highlighting it as key player in the maintenance of genome stability. GCN5 is a coactivator of c-MYC oncogene protein and has oncogenic roles in various cancers.
Specification
Tested Reactivity: Human, mouse, rat
Cited Reactivity: human, mouse, rat
Host / Isotype: Mouse / IgG2a
Class: Monoclonal
Type: Antibody
Immunogen: CatNo: Ag6940 Product name: Recombinant human KAT2A protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 537-837 aa of BC032743 Sequence: EYIARLVFDPKHKTLALIKDGRVIGGICFRMFPTQGFTEIVFCAVTSNEQVKGYGTHLMNHLKEYHIKHNILYFLTYADEYAIGYFKKQGFSKDIKVPKSRYLGYIKDYEGATLMECELNPRIPYTELSHIIKKQKEIIKKLIERKQAQIRKVYPGLSCFKEGVRQIPVESVPGIRETGWKPLGKEKGKELKDPDQLYTTLKNLLAQIKSHPSAWPFMEPVKKSEAPDYYEVIRFPIDLKTMTERLRSRYYVTRKLFVADLQRVIANCREYNPPDSEYCRCASALEKFFYFKLKEGGLIDK Predict reactive species
Full Name: K(lysine) acetyltransferase 2A
Calculated Molecular Weight: 94 kDa
Observed Molecular Weight: 94 kDa
GenBank Accession Number: BC032743
Gene Symbol: KAT2A
Gene ID (NCBI): 2648
RRID: AB_2881935
Conjugate: Unconjugated
Form: Liquid
Purification Method: Protein A purification
UNIPROT ID: Q92830
Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.
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Collaboration
Tony Tang
Email: Tony.Tang@iright.com
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