Proteintech, 66619-1-Ig, Adiponectin receptor 1 Monoclonal antibody

Size: 20ul / 150ul The Adiponectin receptor 1 (66619-1-Ig) by Proteintech is a Monoclonal antibody targeting Adiponectin receptor 1 in WB, ELISA applications with reactivity to Human samples 66619-1-Ig targets Adiponectin receptor 1 in WB, IHC, ELISA applications and shows reactivity with Human samples. Tested Applications Positive WB detected in: HeLa cells, HEK-293 cells, L02 cells, HepG2 cells Recommended dilution Western Blot (WB): WB : 1:1000-1:6000 Background Information Adiponectin is a hormone secreted by adipocytes that acts as an antidiabetic and anti-atherogenic adipokine. Two receptors for adiponectin have been identified: adiponectin receptor 1 (AdipoR1) and adiponectin receptor 2 (AdipoR2). They are seven-transmembrane domain receptors and mediate increased AMPK, MAPK and PPARA ligand activity in response to adiponectin. AdipoR1 is found in many tissues, being particularly abundant in skeletal muscle, whereas AdipoR2 is predominantly expressed in the liver (PMID: 24417942). AdipoR1 has a high affinity for globular adiponectin and a very low affinity for full-length adiponectin. AdipoR2 has an intermediate affinity for both forms. The human ADIPOR1 gene maps to chromosome 1q32.1, and encodes a 375-amino acid protein with a molecular weight of 43 kDa. This antibody was raised against 1-72aa of human AdipoR1. Specification Tested Reactivity: Human Cited Reactivity: human, mouse, pig Host / Isotype: Mouse / IgG1 Class: Monoclonal Type: Antibody Immunogen: CatNo: Ag18187 Product name: Recombinant human ADIPOR1 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 2-72 aa of BC010743 Sequence: SSHKGSVVAQGNGAPASNREADTVELAELGPLLEEKGKRVIANPPKAEEEQTCPVPQEEEEEVRVLTLPLQ Predict reactive species Full Name: adiponectin receptor 1 Calculated Molecular Weight: 375 aa, 43 kDa Observed Molecular Weight: 43 kDa GenBank Accession Number: BC010743 Gene Symbol: Adiponectin receptor 1 Gene ID (NCBI): 51094 RRID: AB_2881979 Conjugate: Unconjugated Form: Liquid Purification Method: Protein G purification UNIPROT ID: Q96A54 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.