Proteintech, 66851-2-Ig, SMO Monoclonal antibody

Size: 20ul / 150ul The SMO (66851-2-Ig) by Proteintech is a Monoclonal antibody targeting SMO in IF/ICC, ELISA applications with reactivity to Human, Canine samples 66851-2-Ig targets SMO in IF/ICC, ELISA applications and shows reactivity with Human, Canine samples. Tested Applications Positive IF/ICC detected in: MDCK cells Recommended dilution Immunofluorescence (IF)/ICC: IF/ICC : 1:400-1:1600 Background Information Smoothened (SMO) is a G protein-coupled receptor that is a component of the hedgehog (Hh) signaling pathway and is conserved from flies to humans. The Hh pathway plays central roles in animal development and stem-cell function. Defects in Hh signalling lead to birth defects and cancer in humans. Expressed on the primary cilium, SMO interacts with the patched protein, a receptor for Hh proteins. Specification Tested Reactivity: Human, Canine Host / Isotype: Mouse / IgG1 Class: Monoclonal Type: Antibody Immunogen: CatNo: Ag25861 Product name: Recombinant human SMO protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 28-233 aa of BC009989 Sequence: RGAASSGNATGPGPRSAGGSARRSAAVTGPPPPLSHCGRAAPCEPLRYNVCLGSVLPYGATSTLLAGDSDSQEEAHGKLVLWSGLRNAPRCWAVIQPLLCAVYMPKCENDRVELPSRTLCQATRGPCAIVERERGWPDFLRCTPDRFPEGCTNEVQNIKFNSSGQCEVPLVRTDNPKSWYEDVEGCGIQCQNPLFTEAEHQDMHSY Predict reactive species Full Name: smoothened homolog (Drosophila) Calculated Molecular Weight: 787 aa, 86 kDa GenBank Accession Number: BC009989 Gene Symbol: SMO Gene ID (NCBI): 6608 RRID: AB_3085033 Conjugate: Unconjugated Form: Liquid Purification Method: Protein G purification UNIPROT ID: Q99835 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.