Product Description
Size: 20ul / 150ul
The DMXL2 (66891-2-Ig) by Proteintech is a Monoclonal antibody targeting DMXL2 in WB, IF/ICC, ELISA applications with reactivity to human, mouse, rat, pig samples
66891-2-Ig targets DMXL2 in WB, IF/ICC, ELISA applications and shows reactivity with human, mouse, rat, pig samples.
Tested Applications
Positive WB detected in: mouse cerebellum tissue, Jurkat cells, rat brain tissue
Positive IF/ICC detected in: Jurkat cells
Recommended dilution
Western Blot (WB): WB : 1:2000-1:10000
Immunofluorescence (IF)/ICC: IF/ICC : 1:400-1:1600
Background Information
DMXL2, also named as rabconnectin-3, is a functional regulator of mammalian notch signaling with WD domains. Rabconnectin-3 is abundantly expressed in the brain where it is enriched in the synaptic vesicle fraction. Immunofluorescence and immunoelectron microscopy revealed that rabconnectin-3 was concentrated on synaptic vesicles at synapses. It may serve as a scaffold molecule for both Rab3 GEP and GAP on synaptic vesicles.
Specification
Tested Reactivity: human, mouse, rat, pig
Host / Isotype: Mouse / IgG2b
Class: Monoclonal
Type: Antibody
Immunogen: CatNo: Ag19861 Product name: Recombinant human DMXL2 protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 573-922 aa of BC140781 Sequence: DSHHTLLHQEGMSVGSPHGSQPHSRSHSTHMNILAPTVMMISKHIDGSLNQWAVTFADKSAFTTVLTVSHKFRYCGHRFHLNDLACHSVLPLLLTSSHHNALLTPELDCQWDSDNKLSRLMDPVKHIKGSSKQPLRNAATRTFHDPNAIYSELILWRVDPIGPLSYTGGVSELARINSLHTSAFSNVAWLPTLIPSYCLGTYCNSASACFVASDGKNLRLYQAVVDARKLLDELSDPESSKLIGEVFNIVSQQSTARPGCIIELDAITNQCGSNTQLLHVFQEDFIIGYKPHKEDMEKKETEIFFQPSQGYRPPPFSEKFFLVVIEKDSNNNSILHMWHLHLKSVQACLG Predict reactive species
Full Name: Dmx-like 2
Calculated Molecular Weight: 3036 aa, 340 kDa
Observed Molecular Weight: 340 kDa
GenBank Accession Number: BC140781
Gene Symbol: DMXL2
Gene ID (NCBI): 23312
RRID: AB_2882221
Conjugate: Unconjugated
Form: Liquid
Purification Method: Protein A purification
UNIPROT ID: Q8TDJ6
Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.
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Collaboration
Tony Tang
Email: Tony.Tang@iright.com
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