Proteintech, 67040-1-Ig, Integrin alpha 4 Monoclonal antibody

Size: 20ul / 150ul The Integrin alpha 4 (67040-1-Ig) by Proteintech is a Monoclonal antibody targeting Integrin alpha 4 in WB, ELISA applications with reactivity to human samples 67040-1-Ig targets Integrin alpha 4 in WB, ELISA applications and shows reactivity with human samples. Tested Applications Positive WB detected in: MOLT-4 cells, Raji cells, U-937 cells, NK-92 cells, THP-1 cells, Jurkat cells Recommended dilution Western Blot (WB): WB : 1:5000-1:50000 Background Information Integrin alpha 4 (ITGA4), also named CD49D, belongs to the integrin alpha chain family. ITGA4 is a receptor for fibronectin, VCAM1, and MADCAM1. ITGA4 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. It recognizes the sequence Q-I-D-S in VCAM1. It recognizes the sequence L-D-T in MADCAM1. On activated endothelial cells ITGA4 triggers homotypic aggregation for most VLA-4-positive leukocyte cell lines. It may also participate in cytolytic T-cell interactions with target cells. Specification Tested Reactivity: human Cited Reactivity: human Host / Isotype: Mouse / IgG2a Class: Monoclonal Type: Antibody Immunogen: CatNo: Ag28024 Product name: Recombinant human Integrin alpha-4 protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 653-1032 aa of BC156712 Sequence: SMKTLMLNVSLFNAGDDAYETTLHVKLPVGLYFIKILELEEKQINCEVTDNSGVVQLDCSIGYIYVDHLSRIDISFLLDVSSLSRAEEDLSITVHATCENEEEMDNLKHSRVTVAIPLKYEVKLTVHGFVNPTSFVYGSNDENEPETCMVEKMNLTFHVINTGNSMAPNVSVEIMVPNSFSPQTDKLFNILDVQTTTGECHFENYQRVCALEQQKSAMQTLKGIVRFLSKTDKRLLYCIKADPHCLNFLCNFGKMESGKEASVHIQLEGRPSILEMDETSALKFEIRATGFPEPNPRVIELNKDENVAHVLLEGLHHQRPKRYFTIVIISSSLLLGLIVLLLISYVMWKAGFFKRQYKSILQEENRRDSWSYINSKSNDD Predict reactive species Full Name: integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) Calculated Molecular Weight: 1032 aa, 115 kDa Observed Molecular Weight: 130-150 kDa GenBank Accession Number: BC156712 Gene Symbol: Integrin alpha 4 Gene ID (NCBI): 3676 RRID: AB_2882354 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: P13612 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.