Product Description
Size: 20ul / 150ul
The GNE (67649-1-Ig) by Proteintech is a Monoclonal antibody targeting GNE in WB, ELISA applications with reactivity to Human, rat samples
67649-1-Ig targets GNE in WB, ELISA applications and shows reactivity with Human, rat samples.
Tested Applications
Positive WB detected in: A549 cells, Hela cells, HEK-293 cells, Jurkat cells, K-562 cells, HSC-T6 cells
Recommended dilution
Western Blot (WB): WB : 1:5000-1:50000
Background Information
The bifunctional enzyme UDP-N-acetylglucosamine-2-epimerase/N-acetylmannosamine kinase (GNE) is essential for early embryonic development and catalyzes the rate limiting step in sialic acid biosynthesis. It plays an important role in neuronal cell and brain development, and is strongly involved in cardiac tissue and skeletal muscle early survival and organization.. This protein has 5 isoforms produced by alternative splicing.
Specification
Tested Reactivity: Human, rat
Cited Reactivity: human
Host / Isotype: Mouse / IgG1
Class: Monoclonal
Type: Antibody
Immunogen: CatNo: Ag18702 Product name: Recombinant human GNE protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 376-722 aa of BC121179 Sequence: SIDLQEPLQKKFCFPPVKENISQDIDHILETLSALAVDLGGTNLRVAIVSMKGEIVKKYTQFNPKTYEERINLILQMCVEAAAEAVKLNCRILGVGISTGGRVNPREGIVLHSTKLIQEWNSVDLRTPLSDTLHLPVWVDNDGNCAALAERKFGQGKGLENFVTLITGTGIGGGIIHQHELIHGSSFCAAELGHLVVSLDGPDCSCGSHGCIEAYASGMALQREAKKLHDEDLLLVEGMSVPKDEAVGALHLIQAAKLGNAKAQSILRTAGTALGLGVVNILHTMNPSLVILSGVLASHYIHIVKDVIRQQALSSVQDVDVVVSDLVDPALLGAASMVLDYTTRRIY Predict reactive species
Full Name: glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
Calculated Molecular Weight: 722 aa, 79 kDa
Observed Molecular Weight: 79 kDa
GenBank Accession Number: BC121179
Gene Symbol: GNE
Gene ID (NCBI): 10020
RRID: AB_2882849
Conjugate: Unconjugated
Form: Liquid
Purification Method: Protein G purification
UNIPROT ID: Q9Y223
Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.
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Collaboration
Tony Tang
Email: Tony.Tang@iright.com
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