Proteintech, 67652-1-Ig, TCF7L1/TCF7L2 Monoclonal antibody

Size: 20ul / 150ul The TCF7L1/TCF7L2 (67652-1-Ig) by Proteintech is a Monoclonal antibody targeting TCF7L1/TCF7L2 in WB, ELISA applications with reactivity to Human, Mouse samples 67652-1-Ig targets TCF7L1/TCF7L2 in WB, ELISA applications and shows reactivity with Human, Mouse samples. Tested Applications Positive WB detected in: HEK-293 cells, HeLa cells, A431 cells, NCCIT cells, JAR cells, NIH/3T3 cells Recommended dilution Western Blot (WB): WB : 1:20000-1:100000 Background Information TCF7L1 is one of TCF/LEF transcription factors that are mediators of the Wnt signaling pathway and are antagonized by the TGF-beta signaling pathway. It binds to DNA and acts as a repressor in the absence of CTNNB1, and as an activator in its presence. It's necessary for the terminal differentiation of epidermal cells, the formation of keratohyalin granules and the development of the barrier function of the epidermis. This antibody raised against 1-200aa of human TCF7L1 can also react with TCF7L2. Specification Tested Reactivity: Human, Mouse Host / Isotype: Mouse / IgG2b Class: Monoclonal Type: Antibody Immunogen: CatNo: Ag28954 Product name: Recombinant human TCF7L1 protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 1-200 aa of BC058894 Sequence: MPQLGGGGGGGGGSGGGGGSSAGAAGGGDDLGANDELIPFQDEGGEEQEPSSDSASAQRDLDEVKSSLVNESENQSSSSDSEAERRPQPVRDTFQKPRDYFAEVRRPQDSAFFKGPPYPGYPFLMIPDLSSPYLSNGPLSPGGARTYLQMKWPLLDVPSSATVKDTRSPSPAHLSNKVPVVQHPHHMHPLTPLITYSNDH Predict reactive species Full Name: transcription factor 7-like 1 (T-cell specific, HMG-box) Calculated Molecular Weight: 63 kDa Observed Molecular Weight: 70 kDa GenBank Accession Number: BC058894 Gene Symbol: TCF7L1 Gene ID (NCBI): 83439 RRID: AB_2882851 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: Q9HCS4 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.