Proteintech, 68135-1-Ig, IL-11 Monoclonal antibody

Size: 20ul / 150ul The IL-11 (68135-1-Ig) by Proteintech is a Monoclonal antibody targeting IL-11 in WB, ELISA applications with reactivity to human samples 68135-1-Ig targets IL-11 in WB, ELISA applications and shows reactivity with human samples. Tested Applications Positive WB detected in: Saos-2 supernatant cells Recommended dilution Western Blot (WB): WB : 1:5000-1:50000 Background Information Interleukin-11 (IL-11) is a member of the glycoprotein-130 (GP-130) cytokines that utilizes the GP-130 signaling pathway shared by other cytokines of the same family. The most well-known role of IL-11 is in hematopoiesis because it promotes megakaryocytopoiesis, erythropoiesis, and thrombopoiesis. In recognition of these properties, human IL-11 recombinant protein (rhIL-11) is used clinically for treating chemotherapy-induced thrombocytopenia. IL-11 has extensive immunomodulatory effects, both anti- and proinflammatory. Specification Tested Reactivity: human Host / Isotype: Mouse / IgG2b Class: Monoclonal Type: Antibody Affinity: K D =1.80 x 10 -9 M K Off =2.20 x 10 -6 M K On =1.22 x 10 3 M Immunogen: CatNo: Ag11199 Product name: Recombinant human IL-11 protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 1-199 aa of BC012506 Sequence: MNCVCRLVLVVLSLWPDTAVAPGPPPGPPRVSPDPRAELDSTVLLTRSLLADTRQLAAQLRDKFPADGDHNLDSLPTLAMSAGALGALQLPGVLTRLRADLLSYLRHVQWLRRAGGSSLKTLEPELGTLQARLDRLLRRLQLLMSRLALPQPPPDPPAPPLAPPSSAWGGIRAALAILGGLHLTLDWAVRGLLLLKTRL Predict reactive species Full Name: interleukin 11 Calculated Molecular Weight: 199 aa, 21 kDa Observed Molecular Weight: 21 kDa GenBank Accession Number: BC012506 Gene Symbol: IL-11 Gene ID (NCBI): 3589 RRID: AB_2923662 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: P20809 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.