Proteintech, 68237-1-Ig, ALDH2 Monoclonal antibody

Size: 20ul / 150ul The ALDH2 (68237-1-Ig) by Proteintech is a Monoclonal antibody targeting ALDH2 in WB, ELISA applications with reactivity to Human, Mouse, Rat, Rabbit, Pig samples 68237-1-Ig targets ALDH2 in WB, ELISA applications and shows reactivity with Human, Mouse, Rat, Rabbit, Pig samples. Tested Applications Positive WB detected in: mouse liver tissue, rabbit liver tissue, rat liver tissue Recommended dilution Western Blot (WB): WB : 1:5000-1:50000 Background Information Acetaldehyde dehydrogenase is the next enzyme after alcohol dehydrogenase in the major pathway of alcohol metabolism. It mediates NADP+-dependent oxidation of aldehydes into acids during detoxification of alcohol-derived acetaldehyde; lipid peroxidation; and metabolism of corticosteroids, biogenic amines and neurotransmitters. Genetic variation in ALDH2 is responsible for individual differences in responses to drinking alcohol. Thus, the absence of this enzyme is linked to alcohol intolerance and a reduced risk for alcoholism-related liver disease. Specification Tested Reactivity: Human, Mouse, Rat, Rabbit, Pig Cited Reactivity: mouse Host / Isotype: Mouse / IgG2a Class: Monoclonal Type: Antibody Immunogen: CatNo: Ag7463 Product name: Recombinant human ALDH2 protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 166-517 aa of BC002967 Sequence: DFFSYTRHEPVGVCGQIIPWNFPLLMQAWKLGPALATGNVVVMKVAEQTPLTALYVANLIKEAGFPPGVVNIVPGFGPTAGAAIASHEDVDKVAFTGSTEIGRVIQVAAGSSNLKRVTLELGGKSPNIIMSDADMDWAVEQAHFALFFNQGQCCCAGSRTFVQEDIYDEFVERSVARAKSRVVGNPFDSKTEQGPQVDETQFKKILGYINTGKQEGAKLLCGGGIAADRGYFIQPTVFGDVQDGMTIAKEEIFGPVMQILKFKTIEEVVGRANNSTYGLAAAVFTKDLDKANYLSQALQAGTVWVNCYDVFGAQSPFGGYKMSGSGRELGEYGLQAYTEVKTVTVKVPQKNS Predict reactive species Full Name: aldehyde dehydrogenase 2 family (mitochondrial) Calculated Molecular Weight: 56 kDa Observed Molecular Weight: 50-55 kDa GenBank Accession Number: BC002967 Gene Symbol: ALDH2 Gene ID (NCBI): 217 RRID: AB_2935324 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: P05091 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.