Product Description
Size: 20ul / 150ul
The GNAI1 (68266-1-Ig) by Proteintech is a Monoclonal antibody targeting GNAI1 in WB, ELISA applications with reactivity to Mouse, Rat, Pig, Chicken samples
68266-1-Ig targets GNAI1 in WB, ELISA applications and shows reactivity with Mouse, Rat, Pig, Chicken samples.
Tested Applications
Positive WB detected in: rat brain tissue, pig brain tissue, chicken brain tissue, mouse brain tissue
Recommended dilution
Western Blot (WB): WB : 1:2000-1:10000
Background Information
The guanine nucleotide-binding protein G(i), α-1 subunit (GNAI1), also known as Gαi-1, belongs to the Gαi family. GNAI1 is an adenylate cyclase inhibitor that modulates cAMP. GNAI1 exerts inhibitory effects on cAMP production through its interaction with GPCR and the inactivation of adenyl cyclase (PMID: 35678269). GNAI1 has 2 isoforms with molecular weights of 35 and 40 kDa, respectively.
Specification
Tested Reactivity: Mouse, Rat, Pig, Chicken
Host / Isotype: Mouse / IgG2b
Class: Monoclonal
Type: Antibody
Immunogen: CatNo: Ag3290 Product name: Recombinant human GNAI1 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-354 aa of BC026326 Sequence: MGCTLSAEDKAAVERSKMIDRNLREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEAGYSEEECKQYKAVVYSNTIQSIIAIIRAMGRLKIDFGDSARADDARQLFVLAGAAEEGFMTAELAGVIKRLWKDSGVQACFNRSREYQLNDSAAYYLNDLDRIAQPNYIPTQQDVLRTRVKTTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVAAIIFCVALSDYDLVLAEDEEMNRMHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKKSPLTICYQEYAGSNTYEEAAAYIQCQFEDLNKRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF Predict reactive species
Full Name: guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
Calculated Molecular Weight: 354 aa, 40 kDa
Observed Molecular Weight: 38-40 kDa
GenBank Accession Number: BC026326
Gene Symbol: GNAI1
Gene ID (NCBI): 2770
RRID: AB_2935351
Conjugate: Unconjugated
Form: Liquid
Purification Method: Protein A purification
UNIPROT ID: P63096
Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.
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Collaboration
Tony Tang
Email: Tony.Tang@iright.com
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