Proteintech, 68394-1-Ig, Protein Z Monoclonal antibody

Size: 20ul / 150ul The Protein Z (68394-1-Ig) by Proteintech is a Monoclonal antibody targeting Protein Z in WB, ELISA applications with reactivity to Human samples 68394-1-Ig targets Protein Z in WB, ELISA applications and shows reactivity with Human samples. Tested Applications Positive WB detected in: human plasma Recommended dilution Western Blot (WB): WB : 1:500-1:2000 Background Information Protein Z (PZ, PROZ) is a vitamin K-dependent plasma protein that serves as a cofactor for activated factor X inhibition by the PZ-dependent protease inhibitor (PMID: 16938126). Reduced circulating levels of PZ have been suggested to play a role in the occurrence of bleeding (PMID: 7495103) and deep vein thrombosis (DVT) (PMID: 10829076), as well as in unexplained abortions with early fetal loss (PMID: 11895801), late fetal demise and intrauterine growth restriction (PMID: 16260213), acute coronary syndromes (PMID: 14652653), and stroke (PMID: 11570404). In addition, PZ may be a biomarker for the early diagnosis of pancreatic cancer (PMID: 31025496). It has two isoforms with molecular weights of 44 kDa and 47 kDa. Specification Tested Reactivity: Human Host / Isotype: Mouse / IgG2a Class: Monoclonal Type: Antibody Immunogen: CatNo: Ag13051 Product name: Recombinant human PROZ protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 23-400 aa of BC074906 Sequence: SVFLPASKANDVLVRWKRAGSYLLEELFEGNLEKECYEEICVYEEAREVFENEVVTDEFWRRYKGGSPCISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNECHPERTDGCQHFCLPGQESYTCSCAQGYRLGEDHKQCVPHDQCACGVLTSEKRAPDLQDLPWQVKLTNSEGKDFCGGVIIRENFVLTTAKCSLLHRNITVKTYFNRTSQDPLMIKITHVHVHMRYDADAGENDLSLLELEWPIQCPGAGLPVCTPEKDFAEHLLIPRTRGLLSGWARNGTDLGNSLTTRPVTLVEGEECGQVLNVTVTTRTYCERSSVAAMHWMDGSVVTREHRGSWFLTGVLGSQPVGGQAHMVLVTKVSRYSLWFKQIMN Predict reactive species Full Name: protein Z, vitamin K-dependent plasma glycoprotein Calculated Molecular Weight: 400 aa, 45 kDa Observed Molecular Weight: 45-47 kDa, 27 kDa GenBank Accession Number: BC074906 Gene Symbol: PROZ Gene ID (NCBI): 8858 RRID: AB_3085111 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: P22891 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.